Tong Meng, Zhang Bo-Cheng, Jia Fei-Yu, Wang Jing, Liu Jing-Hua
Department of General Surgery, Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China.
Graduate Management Office, Education and Teaching Department, Linyi People's Hospital, Linyi 276000, Shandong Province, China.
World J Clin Cases. 2023 Jun 26;11(18):4318-4325. doi: 10.12998/wjcc.v11.i18.4318.
Hepatic inflammatory myofibroblastic tumor (HIMT) is a rare type of hepatic tumor. It is always misdiagnosed and mistreated because it is primarily found with no obvious specific manifestation, and its imaging findings are diverse.
Here, we report a case of HIMT that was initially diagnosed as liver malignancy but was confirmed as HIMT by histopathology after hepatectomy. Mostly, HIMTs are infiltrated with plasma cells and stain positively for anaplastic lymphoma kinase on immunohistochemistry as well as for some other kinases.
HIMT can be treated with single nonsteroidal anti-inflammatory drugs and without surgery when it is diagnosed accurately. Because the etiology of HIMT is unknown and the diagnosis is difficult, the pathogenesis and clinical process need to be further studied.
肝脏炎性肌纤维母细胞瘤（HIMT）是一种罕见的肝脏肿瘤。由于其最初发现时无明显特异性表现，且影像学表现多样，故常被误诊和误治。
在此，我们报告一例HIMT病例，该病例最初被诊断为肝脏恶性肿瘤，但肝切除术后经组织病理学确诊为HIMT。大多数HIMT浸润有浆细胞，免疫组织化学检测间变性淋巴瘤激酶以及其他一些激酶呈阳性染色。
HIMT在准确诊断后可用单一非甾体类抗炎药治疗，无需手术。由于HIMT的病因不明且诊断困难，其发病机制和临床过程有待进一步研究。
