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Progressing from "Whether to" to "How to" Conduct Pragmatic Trials.

作者信息

Casey Jonathan D, Rice Todd W, Semler Matthew W

机构信息

Vanderbilt University Medical Center.

Vanderbilt Institute for Clinical and Translational Research (VICTR).

出版信息

Am J Bioeth. 2023 Aug;23(8):33-36. doi: 10.1080/15265161.2023.2217123.

Abstract
摘要

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本文引用的文献

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Do Clinicians Have a Duty to Participate in Pragmatic Clinical Trials?
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Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19.
Lancet Respir Med. 2022 Jul;10(7):700-714. doi: 10.1016/S2213-2600(22)00044-3. Epub 2022 Jun 13.
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Think Pragmatically: Investigators' Obligations to Patient-Subjects When Research is Embedded in Care.
Am J Bioeth. 2023 Aug;23(8):10-21. doi: 10.1080/15265161.2022.2063435. Epub 2022 Apr 18.
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Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial.
Lancet. 2021 May 29;397(10289):2049-2059. doi: 10.1016/S0140-6736(21)00897-7. Epub 2021 May 14.
7
The PRECIS-2 tool: designing trials that are fit for purpose.
BMJ. 2015 May 8;350:h2147. doi: 10.1136/bmj.h2147.
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Informed consent, comparative effectiveness, and learning health care.
N Engl J Med. 2014 Feb 20;370(8):766-8. doi: 10.1056/NEJMhle1313674.

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