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评价超微半刚性输尿管镜与软性输尿管镜治疗输尿管上段结石的效率和成本:一项前瞻性随机多中心研究。

Evaluation of ultrathin semirigid ureteroscopy in terms of efficiency and cost compared to flexible ureteroscopy in treating proximal ureteric stones: a prospective randomized multicenter study.

机构信息

Urology Department, Faculty of Medicine, Benha University, Benha, Egypt.

Urology Department, Najran Armed Force Hospital, Najran, Saudi Arabia.

出版信息

World J Urol. 2023 Sep;41(9):2527-2534. doi: 10.1007/s00345-023-04507-8. Epub 2023 Jul 21.

Abstract

PURPOSE

To investigate the outcome and cost-effectiveness of ultrathin 6-7.5-Fr semirigid ureteroscopy in treating proximal ureteric stones compared to flexible ureteroscopy.

METHODS

Two hundred and twenty patients with a solitary proximal ureteric stone were eligible for ureteroscopy (stone size = 1-2 cm). Patients were randomly subdivided into two groups: Group I included 105 patients who underwent ultrathin semirigid ureteroscopy and group II included 115 patients who underwent flexible ureteroscopy. Both groups were compared regarding successful stone access, operation time, reoperation rates, the financial cost to stone-free, complications, and stone clearance at 4 and 8 weeks.

RESULTS

Groups I and II had no significant differences regarding patient demographics, stone criteria, and hospitalization time. In contrast, the mean operative time was significantly longer in group II (p < 0.001). The overall scope-to-stone access rate was 89.5%. It was 87.6% compared to 91.3% (p = 0.32), while the stone-free rate was 81.9% versus 87.8% (p = 0.22) for groups I and II, respectively. Intraoperative and postoperative complications were statistically insignificant between the study groups. The cost/person in Egyptian pounds was 8619 ± 350 in group I, compared to 17,620 ± 280 in group II (p < 0.001); similarly, the cost to attain the stone-free rate was 8950 ± 720 in group I compared to 17,950 ± 500 in group II.

CONCLUSION

Ultrathin semirigid ureteroscopy is safe, durable, and considered a cost-effective method for treating upper ureteric calculi compared to the flexible ureteroscopy and could be considered a first treatment option in developing countries.

摘要

目的

研究超硬 6-7.5Fr 半刚性输尿管镜治疗输尿管上段结石的效果和成本效益,与软性输尿管镜相比。

方法

220 例单一输尿管上段结石患者符合输尿管镜检查条件(结石大小=1-2cm)。患者随机分为两组:组 I 包括 105 例接受超硬半刚性输尿管镜治疗的患者,组 II 包括 115 例接受软性输尿管镜治疗的患者。比较两组的结石进入成功率、手术时间、再手术率、达到无石状态的费用、并发症以及 4 周和 8 周时的结石清除率。

结果

两组在患者人口统计学、结石标准和住院时间方面无显著差异。然而,组 II 的平均手术时间明显较长(p<0.001)。总体来看,镜下进入结石的成功率为 89.5%。与 91.3%相比,组 I 为 87.6%(p=0.32),而组 I 和组 II 的无石率分别为 81.9%和 87.8%(p=0.22)。两组之间术中及术后并发症无统计学差异。组 I 中每个人的费用(以埃及镑计算)为 8619±350,而组 II 为 17620±280(p<0.001);同样,组 I 达到无石率的费用为 8950±720,而组 II 为 17950±500。

结论

与软性输尿管镜相比,超硬半刚性输尿管镜治疗输尿管上段结石安全、耐用且具有成本效益,可考虑作为发展中国家的首选治疗方法。

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