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变应性支气管肺曲霉病表现为完全性肺塌陷伴呼吸衰竭。

Allergic bronchopulmonary aspergillosis presenting as complete lung collapse with respiratory failure.

机构信息

Department of Pulmonary Medicine, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India.

Department of Pulmonary Medicine, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India

出版信息

BMJ Case Rep. 2023 Jul 24;16(7):e252828. doi: 10.1136/bcr-2022-252828.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an allergic fungal disease that commonly complicates the natural course of patients with asthma and cystic fibrosis. Patients with ABPA commonly present with recurrent pulmonary infiltrates or bronchiectasis. They also experience difficulty treating asthma. Characteristic radiological findings include central bronchiectasis and high-attenuation mucus. Complete unilateral lung collapse is an uncommon presentation of ABPA, with few cases reported in published literature. We present a case of a man in his mid-40s, with acute cerebrovascular disease, who subsequently developed neurological deterioration, compounded by development of respiratory failure attributed to a complete left lung collapse, requiring invasive mechanical ventilation. Initially suspected to have aspiration pneumonia, he was eventually diagnosed with ABPA and was treated accordingly. This case illustrates an uncommon aetiology for complete lung collapse in this clinical setting and serves to remind us to consider ABPA as a differential diagnosis in such patients as well.

摘要

变应性支气管肺曲霉病(ABPA)是一种变应性真菌感染病,常使哮喘和囊性纤维化患者的病情复杂化。ABPA 患者常表现为反复肺部浸润或支气管扩张。他们也难以治疗哮喘。特征性影像学表现包括中央支气管扩张和高衰减黏液。完全性单侧肺不张是 ABPA 的一种不常见表现,在已发表的文献中报道的病例很少。我们报告了一例 40 多岁的男性,患有急性脑血管病,随后出现神经恶化,同时因完全性左肺不张导致呼吸衰竭,需要进行有创机械通气。最初怀疑为吸入性肺炎,最终被诊断为 ABPA,并进行了相应的治疗。该病例说明了在这种临床情况下完全性肺不张的一种不常见病因,并提醒我们在这些患者中也要考虑 ABPA 作为鉴别诊断。

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