Freeny P C
Postgrad Med. 1986 Sep 1;80(3):139-46, 149, 152-6. doi: 10.1080/00325481.1986.11699518.
Double-contrast barium examination of the colon can demonstrate the changes associated with inflammatory bowel disease more completely and specifically than the single-contrast barium study. However, endoscopy is slightly more sensitive than double-contrast examination for detection of disease. In general, between 18% and 20% of patients with Crohn's disease or ulcerative colitis may be expected to have normal radiographic findings but endoscopically detectable disease. However, most false-negative double-contrast colon studies are associated with mild or minimal findings at proctosigmoidoscopy. Although double-contrast radiography may be less sensitive than endoscopy in detection of inflammatory bowel disease, it has similar accuracy for classification and differentiation. Most studies indicate an accuracy of 95% to 98% in differentiating Crohn's disease and ulcerative colitis, due to the fact that morphologic changes detected by the double-contrast mucosal study rarely overlap in the two diseases. Double-contrast barium examination and endoscopy are complementary studies, and the use of both may provide valuable information for evaluation of patients with suspected inflammatory bowel disease.
与单对比钡剂造影检查相比，结肠双对比钡剂检查能够更全面、更确切地显示与炎症性肠病相关的改变。然而，在内镜检查对疾病的检测方面，其敏感性略高于双对比检查。一般而言，预计患有克罗恩病或溃疡性结肠炎的患者中，有18%至20%的人可能会有正常的放射学表现，但内镜检查可发现疾病。不过，大多数双对比结肠检查的假阴性结果与直肠乙状结肠镜检查时发现的轻度或微小病变有关。尽管双对比造影在炎症性肠病的检测方面可能不如内镜检查敏感，但在分类和鉴别方面具有相似的准确性。大多数研究表明，在鉴别克罗恩病和溃疡性结肠炎方面，准确率为95%至98%，这是因为双对比黏膜检查所发现的形态学改变在这两种疾病中很少重叠。双对比钡剂检查和内镜检查是互补性检查，两者结合使用可为疑似炎症性肠病患者的评估提供有价值的信息。
