体重指数与甲状腺癌的病理特征之间的关系。
RELATIONSHIP BETWEEN BODY MASS INDEX AND PATOHISTOLOGICAL FEATURES OF THYROID CANCER.
机构信息
Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia.
Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia.
出版信息
Acta Clin Croat. 2022 Nov;61(3):469-475. doi: 10.20471/acc.2022.61.03.11.
Available studies report conflicting results on the association of body mass index (BMI) and pathohistological features of thyroid cancer. This study aimed to investigate the relationship between BMI and the pathohistological features of different thyroid cancer types. We analyzed the following data from 95 patients with thyroid cancer: age, gender, BMI, pathohistological characteristics of cancer (tumor size, multifocality, lymphovascular invasion, extrathyroidal invasion) and the presence of regional metastases. The BMI of all patients with thyroid cancer was 27.1 ± 4.2. Significantly more patients with obesity class I had cancer size less than 2 cm (p = 0.02). There is a significant association between BMI and extrathyroid invasion (p = 0.03; OR, 1.18), but not with lymphovascular invasion, tumor size, and multifocality. We can conclude that although obesity is a risk factor for the development of thyroid cancer, higher BMI is only partially associated with more aggressive pathohistological features of thyroid cancer.
现有研究报告称，体重指数（BMI）与甲状腺癌的病理特征之间的关联结果相互矛盾。本研究旨在探讨 BMI 与不同类型甲状腺癌的病理特征之间的关系。我们分析了 95 例甲状腺癌患者的以下数据：年龄、性别、BMI、癌症的病理特征（肿瘤大小、多灶性、血管淋巴管侵犯、甲状腺外侵犯）和区域转移的存在情况。所有甲状腺癌患者的 BMI 为 27.1 ± 4.2。患有 I 级肥胖症的患者中，肿瘤小于 2 厘米的比例明显更高（p = 0.02）。BMI 与甲状腺外侵犯之间存在显著相关性（p = 0.03；OR，1.18），但与血管淋巴管侵犯、肿瘤大小和多灶性无关。我们可以得出结论，尽管肥胖是甲状腺癌发展的危险因素，但较高的 BMI 仅与甲状腺癌更具侵袭性的病理特征部分相关。
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