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左乙拉西坦诱发尖端扭转型室速的罕见表现

A Rare Presentation of Levetiracetam-Induced Torsades De Pointes.

作者信息

Mann Henry, Kusayev Josef, Pandey Sagar, Aryal Binit, Solaimanzadeh Isaac

机构信息

Internal Medicine, One Brooklyn Health System Interfaith Medical Center, Brooklyn, USA.

Medicine, New York Medical College, Valhalla, USA.

出版信息

Cureus. 2023 Jun 23;15(6):e40866. doi: 10.7759/cureus.40866. eCollection 2023 Jun.

Abstract

Torsades de pointes occurs in the presence of a prolonged QTc interval, which has many congenital and acquired causes. Levetiracetam is a widely used anti-epileptic medication secondary to its favorable safety profile. We present a rare case of a 59-year-old male who developed torsades de pointes and cardiac arrest after levetiracetam administration. To our knowledge, there is only one other case report documenting torsades de pointes after levetiracetam administration, and our case report will be the first documenting cardiac arrest after levetiracetam administration.

摘要

尖端扭转型室速发生于QTc间期延长的情况下,QTc间期延长有许多先天性和后天性原因。左乙拉西坦因其良好的安全性而成为一种广泛使用的抗癫痫药物。我们报告一例罕见病例,一名59岁男性在服用左乙拉西坦后发生尖端扭转型室速和心脏骤停。据我们所知,仅有另一例记录左乙拉西坦给药后发生尖端扭转型室速的病例报告,而我们的病例报告将是首例记录左乙拉西坦给药后发生心脏骤停的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db0b/10365144/2759ff895a0d/cureus-0015-00000040866-i01.jpg

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