[儿童结膜肿瘤：262例组织病理学诊断]
[Conjunctival tumors in children : Histopathological diagnoses in 262 cases].
作者信息
Nüßle Simone, Glegola Mateusz, Schulz Tabea, Lagrèze Wolf, Reinhard Thomas, Auw-Hädrich Claudia
机构信息
Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.
Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Freiburg, Deutschland.
出版信息
Ophthalmologie. 2023 Aug;120(8):804-810. doi: 10.1007/s00347-023-01896-4. Epub 2023 Jul 26.
BACKGROUND
The spectrum of conjunctival tumors in children and adolescents significantly differs from that of adults.
OBJECTIVE
The aim of this study was to show the distribution of histopathological diagnoses of pediatric conjunctival tumors.
MATERIAL AND METHODS
Retrospective case series including all conjunctival tumors of children and adolescents under 18 years of age examined histologically over a period of 25 years (1990-2015) at the Eye Center in Freiburg, Germany.
RESULTS
Among the 262 conjunctival specimens, the most common diagnoses were conjunctival nevi (148, [56%]), most often with junctional activity (106/148, [72%]), pyogenic granulomas (26, [10%]), and dermolipomas (18, [7%]). In one case a malignant tumor (conjunctival melanoma) was detected (1, < 1%).
CONCLUSION
The results suggest that pediatric conjunctival tumors are benign in most cases. Most of them were of melanocytic origin, with a junctional conjunctival nevus being the most common diagnosis.
背景
儿童和青少年结膜肿瘤的谱系与成人显著不同。
目的
本研究的目的是展示儿童结膜肿瘤组织病理学诊断的分布情况。
材料与方法
回顾性病例系列研究，纳入了1990年至2015年期间在德国弗赖堡眼科中心接受组织学检查的所有18岁以下儿童和青少年的结膜肿瘤。
结果
在262份结膜标本中，最常见的诊断为结膜痣（148例，[56%]），最常伴有交界性活动（106/148，[72%]）、化脓性肉芽肿（26例，[10%]）和皮样脂肪瘤（18例，[7%]）。有1例检测到恶性肿瘤（结膜黑色素瘤）（1例，<1%）。
结论
结果表明，儿童结膜肿瘤在大多数情况下是良性的。其中大多数起源于黑素细胞，交界性结膜痣是最常见的诊断。
Zotero 插件