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使用多排螺旋计算机断层扫描通过耻骨骨密度对成人进行法医年龄估计。

Forensic age estimation in adults by pubic bone mineral density using multidetector computed tomography.

作者信息

Luo Shuai, Fan Fei, Zhang Xing-Tao, Liu An-Jie, Lin Yu-Shan, Cheng Zi-Qi, Song Chang-Xing, Wang Jun-Jing, Deng Zhen-Hua, Zhan Meng-Jun

机构信息

Department of Forensic Pathology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China.

University of Electronic Science and Technology of China, Chengdu, 611731, Sichuan, China.

出版信息

Int J Legal Med. 2023 Sep;137(5):1527-1533. doi: 10.1007/s00414-023-03067-1. Epub 2023 Jul 26.

Abstract

Radiology plays a crucial role in forensic anthropology for age estimation. However, most studies rely on morphological methods. This study aims to investigate the feasibility of using pubic bone mineral density (BMD) as a new age estimation method in the Chinese population. 468 pubic bone CT scans from living individuals in a Chinese hospital aged 18 to 87 years old were used to measure pubic BMD. The BMD of the bilateral pubic bone was measured using the Mimics software on cross-sectional CT images and the mean BMD of the bilateral pubic bone was also calculated. Regression analysis was performed to assess the correlation between pubic BMD and chronological age and to develop mathematical models for age estimation. We evaluated the accuracy of the best regression model using an independent validation sample by calculating the mean absolute error (MAE). Among all established models, the cubic regression model had the highest R value in both genders, with R = 0.550 for males and R = 0.634 for females. The results of the best model test showed that the MAE for predicting age using pubic BMD was 8.66 years in males and 7.69 years in females. This study highlights the potential of pubic BMD as a useful objective indicator for adult age estimation and could be used as an alternative in forensic practice when other better indicators are lacking.

摘要

放射学在法医人类学的年龄估计中起着至关重要的作用。然而,大多数研究依赖于形态学方法。本研究旨在探讨在中国人群中使用耻骨骨密度(BMD)作为一种新的年龄估计方法的可行性。使用了来自中国一家医院的468例年龄在18至87岁的活体个体的耻骨CT扫描图像来测量耻骨骨密度。在横断面CT图像上使用Mimics软件测量双侧耻骨的骨密度,并计算双侧耻骨的平均骨密度。进行回归分析以评估耻骨骨密度与实际年龄之间的相关性,并建立年龄估计的数学模型。我们通过计算平均绝对误差(MAE),使用独立验证样本评估最佳回归模型的准确性。在所有建立的模型中,三次回归模型在两性中均具有最高的R值,男性R = 0.550,女性R = 0.634。最佳模型测试结果表明,使用耻骨骨密度预测年龄时,男性的MAE为8.66岁,女性为7.69岁。本研究强调了耻骨骨密度作为成人年龄估计有用客观指标的潜力,并且在缺乏其他更好指标时可在法医实践中用作替代方法。

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