Yang Jing, Li Huimin, Gao Jin
Department of Radiation Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Department of Medical Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Heliyon. 2023 Jul 11;9(7):e18149. doi: 10.1016/j.heliyon.2023.e18149. eCollection 2023 Jul.
Spindle cell hemangioendothelioma (SCH) is extremely rare. Only four cases have been reported in the spinal cord (Mahdavi et al., 1996; Abdullah et al., 2002; Nasser et al., 2016; Talan-Hranilović et al., 2007) [1-4]. In addition to surgery, radiotherapy is another effective treatment for spinal cord SCH. Two patients received radiotherapy to a total dose of 50-55Gy and benefited from it. For the treatment of this benign tumor, no one has tried to lower the radiation dose so far. Description:We report a 56-year-old man with extramedullary subdural SCH located in the T10-T11 spinal cord. Low back pain and muscle weakness are the main manifestations. Postoperative follow-up MRI examinations were performed three months after surgery showed residual tumors, he subsequently received radiotherapy and benefited from it. We gave a radiation dose of 40Gy for the first time. The neurological symptoms completely returned to normal four months after radiotherapy, and no recurrence occurred in the follow-up of 24 months. : Epidural lesions are more likely to occur in the upper segment of the thoracic spine for SCH. For patients with inoperable or residual surgery and deep tumors located in the functional area, radiotherapy can be used as the main treatment method. A total radiation dose of 40Gy could achieve good control of SCH and greatly reduce the probability of spinal cord injury.
梭形细胞血管内皮瘤(SCH)极为罕见。仅4例脊髓SCH病例被报道(Mahdavi等人,1996年;Abdullah等人,2002年;Nasser等人,2016年;Talan-Hranilović等人,2007年)[1-4]。除手术外,放射治疗是脊髓SCH的另一种有效治疗方法。两名患者接受了总剂量为50-55Gy的放射治疗并从中受益。对于这种良性肿瘤的治疗,目前尚无尝试降低放射剂量的情况。描述:我们报告一名56岁男性,髓外硬膜下SCH位于T10-T11脊髓节段。主要表现为腰痛和肌肉无力。术后三个月进行的MRI随访检查显示有残留肿瘤,随后他接受了放射治疗并从中受益。我们首次给予40Gy的放射剂量。放射治疗四个月后神经症状完全恢复正常,在24个月的随访中未出现复发。:SCH的硬膜外病变更易发生于胸椎上段。对于无法手术或术后有残留以及位于功能区的深部肿瘤患者,放射治疗可作为主要治疗方法。40Gy的总放射剂量可实现对SCH的良好控制并大幅降低脊髓损伤的概率。