School of Medicine, Wayne State University, Detroit, MI 48202, USA.
Long School of Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
Curr Oncol. 2023 Jul 22;30(7):7019-7030. doi: 10.3390/curroncol30070509.
Lung cancer is the most common cancer killer in the world. The standard of care for surgical treatment of non-small cell lung cancer has been lobectomy. Recent studies have identified that sublobar resection has non-inferior survival rates compared to lobectomy, however. Sublobar resection may increase the number of patients who can tolerate surgery and reduce postoperative pulmonary decline. Sublobar resection appears to have equivalent results to surgery in patients with small, peripheral tumors and no lymph node disease. As the utilization of segmentectomy increases, there may be some centers that perform this operation more than other centers. Care must be taken to ensure that all patients have access to this modality. Future investigations should focus on examining the outcomes from segmentectomy as it is applied more widely. When employed on a broad scale, morbidity and survival rates should be monitored. As segmentectomy is performed more frequently, patients may experience improved postoperative quality of life while maintaining the same oncologic benefit.
肺癌是全球最常见的癌症杀手。非小细胞肺癌手术治疗的标准方法一直是肺叶切除术。然而，最近的研究表明，与肺叶切除术相比，亚肺叶切除术具有非劣效的生存率。亚肺叶切除术可能会增加更多能够耐受手术和减少术后肺部下降的患者数量。对于小型、周边肿瘤且无淋巴结疾病的患者，亚肺叶切除术与手术的结果似乎相当。随着段切除术的应用增加，可能会有一些中心比其他中心更常进行这种手术。必须注意确保所有患者都可以获得这种治疗方式。未来的研究应重点关注段切除术的应用更广泛时的结果。当广泛应用时，应监测发病率和生存率。随着段切除术的更频繁应用，患者可能在保持相同的肿瘤学获益的同时，提高术后生活质量。
