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泌尿科医生对低危前列腺癌进行主动监测的使用情况是否与对小肾肿瘤进行主动监测的使用情况相符?

Does Urologist-level Utilization of Active Surveillance for Low-risk Prostate Cancer Correspond with Utilization of Active Surveillance for Small Renal Masses?

机构信息

Department of Urology, Wayne State University, Detroit, MI, USA.

Department of Urology, Wayne State University, Detroit, MI, USA.

出版信息

Eur Urol. 2024 Feb;85(2):101-104. doi: 10.1016/j.eururo.2023.07.005. Epub 2023 Jul 26.

Abstract

Active surveillance (AS) for prostate cancer (CaP) or small renal masses (SRMs) helps in limiting the overtreatment of indolent malignancies. Implementation of AS for these conditions varies substantially across individual urologists. We examined the Michigan Urological Surgery Improvement Collaborative (MUSIC) registry to assess for correlation of AS between patients with low-risk CaP and patients with SRM managed by individual urologists. We identified 27 urologists who treated at least ten patients with National Comprehensive Cancer Network low-risk CaP and ten patients with SRMs between 2017 and 2021. For surgeons in the lowest quartile of AS use for low-risk CaP (<74%), 21% of their patients with SRMs were managed with AS, in comparison to 74% of patients of surgeons in the highest quartile (>90%). There was a modest positive correlation between the surgeon-level risk-adjusted proportions of patients managed with AS for low-risk CaP and for SRMs (Pearson correlation coefficient 0.48). A surgeon's tendency to use AS to manage one low-risk malignancy corresponds to their use of AS for a second low-risk condition. By identifying and correcting structural issues associated with underutilization of AS, interventions aimed at increasing AS use may have effects that influence clinical tendencies across a variety of urologic conditions. PATIENT SUMMARY: The use of active surveillance (AS) for patients with low-risk prostate cancer or small kidney masses varies greatly among individual urologists. Urologists who use AS for low-risk prostate cancer were more likely to use AS for patients with small kidney masses, but there is room to improve the use of AS for both of these conditions.

摘要

主动监测 (AS) 可用于前列腺癌 (CaP) 或小肾肿瘤 (SRMs),有助于减少对惰性恶性肿瘤的过度治疗。不同的泌尿科医生对这些情况实施 AS 的情况差异很大。我们检查了密歇根州泌尿外科学术改进合作组织 (MUSIC) 登记处,以评估个体泌尿科医生管理的低危 CaP 患者和 SRM 患者之间 AS 的相关性。我们确定了 27 名泌尿科医生,他们在 2017 年至 2021 年间至少治疗了 10 名患有国家综合癌症网络低危 CaP 的患者和 10 名患有 SRM 的患者。对于低危 CaP 中 AS 使用率最低(<74%)的四分位数医生,他们的 SRM 患者中有 21%接受 AS 治疗,而四分位数最高(>90%)的医生的患者中有 74%接受 AS 治疗。低危 CaP 和 SRM 中接受 AS 治疗的患者的风险调整比例与医生水平之间存在适度的正相关(Pearson 相关系数 0.48)。一位外科医生管理一种低危恶性肿瘤的 AS 倾向与其管理第二种低危疾病的 AS 倾向相对应。通过识别和纠正与 AS 应用不足相关的结构性问题,旨在增加 AS 应用的干预措施可能会对各种泌尿科疾病的临床倾向产生影响。

患者总结

个体泌尿科医生在低危前列腺癌或小肾癌患者中使用主动监测 (AS) 的差异很大。使用 AS 治疗低危前列腺癌的泌尿科医生更有可能使用 AS 治疗小肾癌患者,但在这两种情况下,AS 的应用都有改进的空间。

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