Stangl Fabian P, Schneidewind Laila, Wagenlehner Florian M, Schultz-Lampel Daniela, Baeßler Kaven, Naumann Gert, Schönburg Sandra, Anheuser Petra, Winkelhog-Gran Susanne, Saar Matthias, Hüsch Tanja, Kranz Jennifer
Department of Urology, University Hospital of Bern, 3010 Bern, Switzerland.
Department of Urology, University Medical Centre Rostock, 18057 Rostock, Germany.
Antibiotics (Basel). 2023 Jul 22;12(7):1219. doi: 10.3390/antibiotics12071219.
Antibiotic prophylaxis contributes substantially to the increase in antibiotic resistance rates worldwide. This investigation aims to assess the current standard of practice in using antibiotic prophylaxis for urodynamics (UDS) and identify barriers to guideline adherence. An online survey using a 22-item questionnaire designed according to the Checklist for Reporting Results of Internet E-Surveys (CHERRIES) was circulated among urologists and gynecologists in Austria, Germany, and Switzerland between September 2021 and March 2022. A total of 105 questionnaires were eligible for analysis. Out of 105 completed surveys, most responders ( = 99, 94%) regularly perform dipstick urine analysis prior to urodynamics, but do not perform a urine culture ( = 68, 65%). Ninety-eight (93%) participants refrain from using antibiotic prophylaxis, and sixty-eight (65%) use prophylaxis if complicating factors exist. If asymptomatic bacteriuria is present, approximately 54 (52%) participants omit UDS and reschedule the procedure until antimicrobial susceptibility testing is available. Seventy-eight (78%) participants do not have a standard procedure for antibiotic prophylaxis in their department. Part of the strategy against the development of bacterial resistance is the optimized use of antibiotics, including antibiotic prophylaxis in urodynamics. Establishing a standard procedure is necessary and purposeful to harmonize both aspects in the field of urological diagnostics.
抗生素预防在全球范围内对抗生素耐药率的上升起到了很大作用。本研究旨在评估目前在尿动力学检查（UDS）中使用抗生素预防的实践标准，并确定遵循指南的障碍。2021年9月至2022年3月期间，在奥地利、德国和瑞士的泌尿科医生和妇科医生中开展了一项在线调查，该调查使用了一份根据互联网电子调查结果报告清单（CHERRIES）设计的包含22个条目的问卷。共有105份问卷符合分析条件。在105份完成的调查中，大多数受访者（n = 99，94%）在尿动力学检查前常规进行尿试纸分析，但不进行尿培养（n = 68，65%）。98名（93%）参与者避免使用抗生素预防，68名（65%）参与者在存在复杂因素时使用预防措施。如果存在无症状菌尿，约54名（52%）参与者会取消尿动力学检查，并重新安排检查时间，直到获得抗菌药物敏感性测试结果。78名（78%）参与者所在科室没有抗生素预防的标准程序。对抗细菌耐药性发展的部分策略是优化抗生素的使用，包括在尿动力学检查中使用抗生素预防。建立标准程序对于协调泌尿外科诊断领域的这两个方面是必要且有意义的。
