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假激酶、 Tribbles 蛋白与癌症

Pseudokinases, Tribbles Proteins and Cancer.

作者信息

Velasco Guillermo, Link Wolfgang

机构信息

Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, 28040 Madrid, Spain.

Instituto de Investigaciones Sanitarias San Carlos (IdISSC), 28040 Madrid, Spain.

出版信息

Cancers (Basel). 2023 Jul 9;15(14):3547. doi: 10.3390/cancers15143547.

Abstract

The human kinome comprises 518 protein kinases, of which approximately 10% lack one or more of the conserved amino acids necessary for catalytic activity [...].

摘要

人类激酶组包含518种蛋白激酶,其中约10%缺少催化活性所必需的一种或多种保守氨基酸[……]。

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引用本文的文献

本文引用的文献

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The Critical Role of TRIB2 in Cancer and Therapy Resistance.
Cancers (Basel). 2021 May 30;13(11):2701. doi: 10.3390/cancers13112701.
6
Tribbles Pseudokinase 3 Regulation and Contribution to Cancer.
Cancers (Basel). 2021 Apr 11;13(8):1822. doi: 10.3390/cancers13081822.
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Control of Cell Growth and Proliferation by the Tribbles Pseudokinase: Lessons from Drosophila.
Cancers (Basel). 2021 Feb 20;13(4):883. doi: 10.3390/cancers13040883.
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