Loffroy Romaric, Mazit Amin, Comby Pierre-Olivier, Falvo Nicolas, Tinel Claire, Chevallier Olivier
Department of Vascular and Interventional Radiology, Image-Guided Therapy Center, François-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, France.
ICMUB Laboratory, UMR CNRS 6302, University of Burgundy, 21078 Dijon, France.
Biomedicines. 2023 Jul 7;11(7):1935. doi: 10.3390/biomedicines11071935.
The primary objective was to evaluate the clinical success rate after endovascular embolization of iatrogenic vascular lesions caused during partial nephrectomy. The secondary objective was to evaluate the technical success and to assess potential effects on renal function. We retrospectively included consecutive patients from our center who underwent selective embolization to treat iatrogenic renal arterial lesions induced during partial nephrectomy between June 2010 and June 2020. The technical and clinical success rates and renal outcomes were collected. We identified 25 patients with 47 pseudoaneurysms and nine arteriovenous fistulas. Among them, eight were treated by coils only, eight by liquid embolization agents only, and nine by both. The technical success rate was 96% after the first attempt and 100% after the second attempt. The median follow-up was 27.1 ± 24.3 months. Clinical success, defined as no need for further hemostatic surgery during follow-up, was also obtained in 96% and 100% of patients with one and two attempts, respectively. Renal function estimated by the modification of diet in renal disease equation did not change significantly despite a mean 13.8% ± 15.1% decrease in kidney functional volume estimated by angiography. No complications were attributable to the endovascular treatment. No significant difference was found across embolization agents; however, the subgroup sizes were small. Endovascular embolization is safe and effective for treating iatrogenic arterial lesions after partial nephrectomy: success rates are high, complications are infrequent, and renal function is maintained. Recommendations by interventional radiology societies are needed to standardize this treatment.
主要目的是评估部分肾切除术中引起的医源性血管病变进行血管内栓塞后的临床成功率。次要目的是评估技术成功率并评估对肾功能的潜在影响。我们回顾性纳入了2010年6月至2020年6月间在本中心接受选择性栓塞治疗部分肾切除术中诱发的医源性肾动脉病变的连续患者。收集技术和临床成功率以及肾脏结局。我们确定了25例患者,其中有47个假性动脉瘤和9个动静脉瘘。其中,8例仅接受弹簧圈治疗,8例仅接受液体栓塞剂治疗,9例接受两者联合治疗。首次尝试后的技术成功率为96%,第二次尝试后为100%。中位随访时间为27.1±24.3个月。分别在首次和第二次尝试的患者中,96%和100%获得了临床成功,定义为随访期间无需进一步的止血手术。尽管通过血管造影术估计的肾脏功能体积平均下降了13.8%±15.1%,但通过肾脏病饮食改良方程估算的肾功能没有显著变化。没有并发症可归因于血管内治疗。在栓塞剂之间未发现显著差异;然而,亚组规模较小。血管内栓塞治疗部分肾切除术后的医源性动脉病变是安全有效的:成功率高,并发症少见,肾功能得以维持。需要介入放射学会的建议来规范这种治疗。