Division of Pediatric Gastroenterology, University of Texas Southwestern Medical Center, Children's Health, Dallas, Texas, USA.
Curr Opin Gastroenterol. 2023 Sep 1;39(5):416-420. doi: 10.1097/MOG.0000000000000955. Epub 2023 Jul 17.
Some children with acute recurrent and chronic pancreatitis stand to benefit from therapeutic endoscopic interventions. The purpose of this review is to summarize specific endoscopic therapies used for these conditions and highlight areas of future research.
Multicenter collaboration and consortium efforts have provided more data now than ever on the technical outcomes and safety of therapeutic endoscopic procedures for pancreatitis in children. Indications are growing but more research is needed to help guide patient selection.
Advanced endoscopic procedures including endoscopic retrograde cholangiopancreatography, endoscopic-ultrasound guided therapies, and single-operator pancreatoscopy may be used in patients with acute recurrent or chronic pancreatitis to manage pancreatic duct obstruction or local complications including pseudocysts and walled-off necrosis. Patient and procedural factors differ between adults and children. Access to these procedures for younger children is growing, and technical outcomes and adverse event rates appear similar between adults and children.
一些患有急性复发性和慢性胰腺炎的儿童可能受益于治疗性内镜介入。本文综述的目的是总结用于这些疾病的特定内镜治疗方法,并强调未来研究的领域。
多中心合作和财团努力为儿童胰腺炎的治疗性内镜手术的技术结果和安全性提供了比以往任何时候都多的数据。适应证在不断增加,但需要更多的研究来帮助指导患者选择。
包括内镜逆行胰胆管造影术、内镜超声引导下治疗和单操作胰胆管镜在内的先进内镜程序可用于治疗急性复发性或慢性胰腺炎患者,以管理胰管阻塞或局部并发症,包括假性囊肿和隔离性坏死。患者和程序因素在成人和儿童之间有所不同。对于年龄较小的儿童,这些程序的应用正在增加,并且成人和儿童之间的技术结果和不良事件发生率似乎相似。