Aberg A, Gislen L
Am J Obstet Gynecol. 1986 Jan;154(1):68-74. doi: 10.1016/0002-9378(86)90395-9.
The present study describes the testing and function of the drop-volume method in the analysis of fetal lung maturity with use of amniotic fluid. Elevated surface tension resulting from a lack of surface-active phospholipids (surfactant) is the primary etiologic defect in the development of respiratory distress syndrome. The drop-volume method quantifies the surface tension of amniotic fluid with use of the fact that the volume of a falling drop of liquid is proportional to the quantity of surfactant in the solution. The drop-volume method requires only 2 minutes and 2 ml of amniotic fluid and predicts fetal lung maturity with an accuracy equal to or greater than that of other tests currently in use.
本研究描述了滴体积法在利用羊水分析胎儿肺成熟度中的测试及功能。由于缺乏表面活性磷脂（表面活性剂）导致的表面张力升高是呼吸窘迫综合征发生发展的主要病因缺陷。滴体积法利用液体滴下的体积与溶液中表面活性剂的量成正比这一事实来量化羊水的表面张力。滴体积法仅需2分钟和2毫升羊水，且预测胎儿肺成熟度的准确性与目前使用的其他测试相当或更高。
