Department of Orthopedic Surgery, Veterans Health Service Medical Center, 53 Jinhwangdo-ro 61-gil, Gangdong-gu, Seoul, 05368, South Korea.
Arch Orthop Trauma Surg. 2023 Dec;143(12):7147-7151. doi: 10.1007/s00402-023-04928-5. Epub 2023 Aug 4.
The relationship between knee osteoarthritis (OA), bone mineral density (BMD), and alignment has not yet been clarified. This study aimed to investigate the relationship between the two limbs in patients with single-limb knee OA.
Patients who underwent single-limb total knee arthroplasty between March 2019 and February 2021 were retrospectively analyzed. Only patients with Kellgren-Lawrence (KL) grades III and IV on the operated side and KL I and II on the opposite side were included. Patients with traumatic OA, a surgery that could change the alignment of both lower extremities and previous fractures were excluded. The proximal femur BMD on the OA and non-OA sides were compared. In addition, the difference in BMD was compared between a group with a difference in alignment of both lower extremities (> 5°) and a group without a difference (< 5°).
In total, 149 patients were included. The BMD T-score of the femoral neck on the OA side was lower than that of the non-OA side (p < 0.001). There was no correlation between BMD and alignment, and there was no difference in BMD according to the difference in alignment.
The femoral neck BMD of the leg on the side with knee OA was lower than that on the side without OA. However, the alignment difference between the legs did not affect BMD. BMD was lowered because of OA and not because of alignment.
膝关节骨关节炎(OA)、骨密度(BMD)和对线之间的关系尚未阐明。本研究旨在探讨单侧膝关节 OA 患者的双下肢之间的关系。
回顾性分析 2019 年 3 月至 2021 年 2 月期间接受单侧全膝关节置换术的患者。仅纳入对侧为 KL I 和 II 级而手术侧为 KL III 和 IV 级的患者。排除创伤性 OA、可能改变双下肢对线的手术和既往骨折的患者。比较 OA 和非 OA 侧的股骨近端 BMD。此外,还比较了下肢对线差异(> 5°)组和无差异(< 5°)组之间的 BMD 差异。
共纳入 149 例患者。OA 侧股骨颈的 BMD T 评分低于非 OA 侧(p < 0.001)。BMD 与对线之间无相关性,且根据对线差异,BMD 无差异。
膝关节 OA 侧下肢的股骨颈 BMD 低于无 OA 侧。然而,下肢对线差异并不影响 BMD。BMD 降低是由于 OA,而不是由于对线。