Babskiĭ V I, Kruglova G V
Med Radiol (Mosk). 1986 Feb;31(2):22-8.
A total of 105 lymphosarcoma patients with primary involvement of retroperitoneal and mesenterial lymph nodes (aged 17 to 77) were examined. Diagnosis was verified on morphology. Chemo- and radiotherapy was administered to 35 (33.3%) patients, chemotherapy alone to 34 (32.3%), combined therapy (surgery combined with radio- and drug therapy) to 20 (19%) patients, gamma-beam therapy to 16 (15.2%) patients. Remissions were achieved in 85.7% of the patients, of them complete remissions in 51.4% of the patients. Seventy patients were followed up prior to recurrences. In 54.2% of the patients recurrences manifested themselves in the generalization of tumor process with involvement of distant peripheral lymph nodes as well as extranodal organs within 1 year of remission irrespective of therapeutic methods. Local recurrences were noted in 73.9% of the patients on chemotherapy. Lymphosarcoma generalization was found in 63.6% of the patients receiving chemotherapy. A 5-year recurrence-free period was noted in 28.5% of the patients receiving combined therapy.