Bierowski Matthew, Galanis Taki, Majeed Amry, Mofid Alireza
Internal Medicine, Thomas Jefferson University Hospital, 1025 Walnut Street, Philadelphia, PA 19107, USA.
Division Vascular Medicine, Jefferson Vascular Center, Sidney Kimmel Medical College, Philadelphia, PA, USA.
Med Clin North Am. 2023 Sep;107(5):823-827. doi: 10.1016/j.mcna.2023.05.008. Epub 2023 Jul 3.
Peripheral artery disease (PAD) affects approximately 230 million people worldwide and is associated with an increased risk of major adverse cardiovascular and limb events. Even though this condition is considered a cardiovascular equivalent, it remains an under-recognized and under-treated entity. Anti-platelet and statin therapy, along with smoking cessation, are the foundations of therapy to reduce adverse events but are challenging to fully implement in this patient population. Race and socioeconomic status also have profound impacts on PAD outcomes. Exercise therapy is the gold standard treatment of claudication while revascularization procedures are often reserved for patients with limb-threatening ischemia.
外周动脉疾病(PAD)在全球约影响2.3亿人,并与主要不良心血管和肢体事件风险增加相关。尽管这种疾病被视为心血管等同病症,但它仍然是一个未得到充分认识和治疗的实体。抗血小板和他汀类药物治疗,以及戒烟,是减少不良事件的治疗基础,但在这一患者群体中全面实施具有挑战性。种族和社会经济地位也对PAD的治疗结果有深远影响。运动疗法是间歇性跛行的金标准治疗方法,而血运重建手术通常仅用于有肢体威胁性缺血的患者。