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体重指数对短节段腰椎后路融合术后融合结果的影响。

Effect of Body Mass Index on Fusion Outcome After Short-Segment Posterior Lumbar Fusion.

作者信息

Safdar Aleeza, Louise Atherton Mara, Motiei-Langroudi Rouzbeh

机构信息

Department of Neurosurgery, University of Kentucky, Lexington, Kentucky, USA.

College of Medicine, University of Kentucky, Lexington, Kentucky, USA.

出版信息

World Neurosurg. 2023 Oct;178:e641-e645. doi: 10.1016/j.wneu.2023.07.136. Epub 2023 Aug 3.

Abstract

OBJECTIVE

Obesity is a growing epidemic in the United States. While many adverse effects of obesity on surgical outcome are well studied, a direct correlation among obesity, pseudarthrosis, and adjacent segment pathology is not well defined. In this study we aimed to identify the effect of body mass index (BMI) on pseudarthrosis, adjacent segment pathology (ASP), and reoperation after short-segment (1-3 levels) open posterior lumbar fusion (PLF).

METHODS

This is a retrospective study of patients with degenerative spine pathologies who underwent 1-, 2-, or 3-level PLF surgery between 2010 and 2020. The relevant medical and imaging records were reviewed, and the following variables were recorded: age, gender, BMI, smoking status, surgical details, follow-up length, need for reoperation, indication for reoperation (pseudarthrosis or occurrence of ASP).

RESULTS

We included363 patients in our study. Twenty-five patients (6.9%) developed pseudarthrosis, 109 (30%) developed ASP, and 104 patients (28.7%) underwent reoperation for either of these reasons. BMI was significantly less in those who developed pseudarthrosis compared with those who did not (28.6 ± 5.5 vs. 31.2 ± 6.2, respectively; P = 0.04). BMI was not significantly different in those who developed ASP or underwent reoperation compared with those who did not (P = 0.06 and 0.08, respectively). Multivariate regression analysis showed none of the variables in the model (age, gender, tobacco use, BMI, and its classes) significantly predicted pseudarthrosis, ASP, or reoperation (P > 0.1 for all variables).

CONCLUSIONS

Obese patients undergoing short-segment open PLF have comparable results in terms of pseudarthrosis, ASP, and reoperation.

摘要

目的

肥胖在美国正成为日益严重的流行病。虽然肥胖对手术结果的许多不良影响已得到充分研究,但肥胖、假关节形成和相邻节段病变之间的直接关联尚未明确界定。在本研究中,我们旨在确定体重指数(BMI)对短节段(1 - 3个节段)开放性后路腰椎融合术(PLF)后假关节形成、相邻节段病变(ASP)和再次手术的影响。

方法

这是一项对2010年至2020年间接受1、2或3节段PLF手术的退行性脊柱疾病患者的回顾性研究。回顾了相关的医学和影像学记录,并记录了以下变量:年龄、性别、BMI、吸烟状况、手术细节、随访时长、再次手术需求、再次手术指征(假关节形成或ASP的发生)。

结果

我们的研究纳入了363例患者。25例(6.9%)发生假关节形成,109例(30%)发生ASP,104例(28.7%)因上述任一原因接受再次手术。发生假关节形成的患者的BMI显著低于未发生者(分别为28.6±5.5和31.2±6.2;P = 0.04)。发生ASP或接受再次手术的患者与未发生者相比,BMI无显著差异(分别为P = 0.06和0.08)。多因素回归分析显示,模型中的变量(年龄、性别、吸烟情况、BMI及其分类)均未显著预测假关节形成、ASP或再次手术(所有变量P>0.1)。

结论

接受短节段开放性PLF手术的肥胖患者在假关节形成、ASP和再次手术方面结果相当。

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