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Editorial: Diverse roles of MAP4K4 in MAP kinase signaling and its implication for cancer therapeutics.

作者信息

Roy Ruchi, Singh Sunil Kumar, Rana Ajay

机构信息

UICentre for Drug Discovery, The University of Illinois at Chicago, Chicago, IL, United States.

Department of Surgery, Division of Surgical Oncology, The University of Illinois at Chicago, Chicago, IL, United States.

出版信息

Front Oncol. 2023 Jul 19;13:1248808. doi: 10.3389/fonc.2023.1248808. eCollection 2023.

Abstract
摘要

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Editorial: Diverse roles of MAP4K4 in MAP kinase signaling and its implication for cancer therapeutics.
Front Oncol. 2023 Jul 19;13:1248808. doi: 10.3389/fonc.2023.1248808. eCollection 2023.
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本文引用的文献

1
MAP4K4 deletion inhibits proliferation and activation of CD4(+) T cell and promotes T regulatory cell generation in vitro.
Cell Immunol. 2014 May-Jun;289(1-2):15-20. doi: 10.1016/j.cellimm.2014.02.006. Epub 2014 Mar 11.
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Rap1 and Rap2 antagonistically control endothelial barrier resistance.
PLoS One. 2013;8(2):e57903. doi: 10.1371/journal.pone.0057903. Epub 2013 Feb 28.
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ShRNA-targeted MAP4K4 inhibits hepatocellular carcinoma growth.
Clin Cancer Res. 2011 Feb 15;17(4):710-20. doi: 10.1158/1078-0432.CCR-10-0331. Epub 2010 Dec 30.
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Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma.
Clin Cancer Res. 2008 Nov 1;14(21):7043-9. doi: 10.1158/1078-0432.CCR-08-0381.
5
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase.
Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3775-80. doi: 10.1073/pnas.0600040103. Epub 2006 Feb 28.

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