Castro-Govea Yanko, García-Garza Jorge A, Vázquez-Lara Sergio E, González-Cantú Cynthia M, Chacón-Moreno Hernán, Cervantes-Kardasch Víctor H
Service of Plastic Surgery, School of Medicine and "Dr. Jose E. González" University Hospital, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico.
Laboratory of Tissue Engineering, Faculty of Medicine, University of Colima, Colima, Mexico.
Arch Plast Surg. 2023 Aug 2;50(4):335-339. doi: 10.1055/a-2067-5481. eCollection 2023 Jul.
It is undeniable that a significant number of patients who want to improve their facial appearance is increasingly interested in nonsurgical procedures. Without a doubt, the use of autologous fat could not be left out as a magnificent alternative for nasal modeling simply because of four influential factors: ease of collection, compatibility, the temporality of the results, and safety. This work describes an innovative alternative technique for nasal modeling using micrografts enriched with adipose-derived mesenchymal stem cells (ASCs). With this technique, fat was collected and divided into two samples, nanofat and microfat. Nanofat was used to isolate the ASCs; microfat was enriched with ASCs and used for nasal modeling. Lipoinjection was performed in a supraperiosteal plane on the nasal dorsum. Through a retrolabial access, the nasal tip and base of the columella were lipoinjected. We consider that nonsurgical nasal modeling using micrografts enriched with ASCs can be an attractive and innovative alternative. This technique will never be a substitute for surgical rhinoplasty. It can be performed in a minor procedure area with rapid recovery and return to the patient's daily activities the next day. If necessary, the procedure can be repeated.
不可否认，相当多想要改善面部外观的患者对非手术方法越来越感兴趣。毫无疑问，自体脂肪因其四个有影响力的因素：采集容易、相容性好、效果的暂时性以及安全性，作为鼻部塑形的绝佳选择不容忽视。这项工作描述了一种使用富含脂肪来源间充质干细胞（ASCs）的微移植进行鼻部塑形的创新替代技术。采用这种技术，脂肪被采集并分成两个样本，纳米脂肪和微脂肪。纳米脂肪用于分离ASCs；微脂肪富含ASCs并用于鼻部塑形。在鼻背的骨膜上平面进行脂肪注射。通过唇后入路，对鼻尖和鼻小柱基部进行脂肪注射。我们认为，使用富含ASCs的微移植进行非手术鼻部塑形可以是一种有吸引力的创新选择。这项技术永远不会替代手术隆鼻术。它可以在一个小手术区域进行，恢复迅速，患者第二天即可恢复日常活动。如有必要，该手术可以重复进行。
