朗格汉斯细胞组织细胞增多症表现出对68Ga-FAPI的强烈摄取。
Langerhans Cell Histiocytosis Showed Intense Uptake of 68 Ga-FAPI.
作者信息
Pan Qingqing, Zhang Hongzhe, Cao Xinxin, Li Jian, Luo Yaping
机构信息
Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.
出版信息
Clin Nucl Med. 2023 Oct 1;48(10):894-895. doi: 10.1097/RLU.0000000000004786. Epub 2023 Aug 3.
A 23-year-old man was recently diagnosed with Langerhans cell histiocytosis (LCH). 68 Ga-FAPI PET/CT showed multiple lesions with intense FAPI uptake in the axial and appendicular skeleton with lytic or mixed bone destruction, consistent with osseous lesions of LCH. FAPI-avid foci around the right atrium and inferior vena cava, as well as micronodules and thin-walled cysts in the lungs, were also noted, possibly also involvement of LCH. This case suggested that 68 Ga-FAPI PET/CT may have the potential to be applied in evaluation of LCH.
一名23岁男性最近被诊断为朗格汉斯细胞组织细胞增多症（LCH）。68Ga-FAPI PET/CT显示，在中轴骨和四肢骨骼中出现多个有强烈FAPI摄取的病灶，并伴有溶骨性或混合性骨质破坏，符合LCH的骨病变表现。同时还注意到右心房和下腔静脉周围有FAPI摄取热点，以及肺部的微小结节和薄壁囊肿，可能也为LCH累及。该病例提示68Ga-FAPI PET/CT可能具有用于评估LCH的潜力。
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