无菌性脑膜脑炎所致脑电图广泛性多棘波模式

Generalized Polyspike Pattern in EEG Due to Aseptic Meningoencephalitis.

作者信息

Hobert Markus A, Dargvainiene Justina, Margraf Nils G

机构信息

Department of Neurology, Christian-Albrecht University of Kiel and University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.

Institute of Clinical Chemistry, Christian-Albrecht University of Kiel and University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.

出版信息

Diagnostics (Basel). 2023 Aug 2;13(15):2569. doi: 10.3390/diagnostics13152569.

DOI:10.3390/diagnostics13152569

PMID:37568932

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10417272/

Abstract

We report the electroencephalography (EEG) showing an intermittent generalized polyspike pattern in EEG due to an aseptic meningoencephalitis in a 71-year-old soporous patient. Initially, she presented with word-finding disturbances and later with generalized tonic-clonic seizures. The cerebrospinal fluid (CSF) showed pleocytosis of 99 leukocytes/μL (primarily neutrophils) and an increased protein level of 1240 mg/L (CSF/serum glucose ratio and lactate unremarkable). Pathogens and autoimmune antibodies in CSF were not found. Brain imaging was unremarkable. After antibiotic, antiviral and anticonvulsive therapy, the pattern in the EEG was no longer detectable. The patient was discharged to go home due to absence of any residues.

摘要

我们报告了一名71岁嗜睡患者因无菌性脑膜脑炎导致脑电图（EEG）显示间歇性全身性多棘波模式。最初，她出现找词困难，随后出现全身性强直阵挛发作。脑脊液（CSF）显示白细胞增多，为99个白细胞/μL（主要为中性粒细胞），蛋白质水平升高至1240 mg/L（CSF/血清葡萄糖比值和乳酸水平无异常）。未在脑脊液中发现病原体和自身免疫抗体。脑部影像学检查无异常。经过抗生素、抗病毒和抗惊厥治疗后，脑电图中的这种模式不再可检测到。由于没有任何后遗症，患者出院回家。