端侧门腔分流术与侧侧肠系膜上腔静脉分流术对犬肝脏血流动力学影响的比较。

A comparison of the effects of end-to-side portacaval shunting and side-to-side mesocaval shunting on hepatic haemodynamics in the dog.

作者信息

Jenkins S A, Taylor A, Johnson J, Shimirty S K, Baxter J N, Shields R

出版信息

Clin Exp Pharmacol Physiol. 1986 Jun;13(6):447-52. doi: 10.1111/j.1440-1681.1986.tb00925.x.

DOI:10.1111/j.1440-1681.1986.tb00925.x

Abstract

Functional liver blood flow and hepatic artery flow were measured before and after either end-to-side portacaval or side-to-side mesocaval shunting in dogs. Functional liver blood fell by approximately 50% following both portacaval and mesocaval shunting. The hepatic artery response was variable after both portacaval and mesocaval shunts. It is concluded that side-to-side mesocaval shunts do not preserve hepatic blood flow or produce a greater compensatory increase in hepatic artery flow than conventional portacaval shunts.

摘要

在犬类动物中，于端侧门腔分流术或侧侧肠系膜上腔静脉分流术前后分别测量功能性肝血流量和肝动脉血流量。门腔分流术和肠系膜上腔静脉分流术后，功能性肝血流量均下降约50%。门腔分流术和肠系膜上腔静脉分流术后肝动脉的反应各不相同。得出的结论是，与传统的门腔分流术相比，侧侧肠系膜上腔静脉分流术并不能维持肝血流量，也不会使肝动脉血流量产生更大的代偿性增加。