Zhang B, Ding J H
Department of Colorectal Surgery, the Characteristic Medical Center of PLA Rocket Force, Beijing 100088, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2023 Jun 25;26(6):607-613. doi: 10.3760/cma.j.cn441530-20230310-00076.
Intersphincteric resection (ISR) has been performed as an ultimate sphincter-sparing strategy in selected patients with low rectal cancer. Accumulating evidence suggests that ISR may be an interesting alternative to abdominoperineal resection to avoid a permanent stoma without compromising oncological outcomes. However, bowel dysfunction is a most common consequence of ISR not to be neglected. To date, limited clinical research has reported functional and quality of life outcomes according to patient-reported outcome measures. Also, data concerning management of low anterior resection syndrome are scarce due to lack of quality evidence. Therefore, this review provides an up-to-date summary of systematic assessment (including function, quality of life, manometry and morphology) and bowel rehabilitation for ISR patients. Postoperative anal function is often assessed by a combination of scales, including the Incontinence Assessment Scale, the Gastrointestinal Function Questionnaire, the Specific LARS Assessment Scale and the Faecal Diary. The condition-specific Quality of Life Scale is more appropriate for Quality-of-life measures in fecal incontinence after ISR. Patients' physiological function after ISR can be assessed using water- or high-resolution solid-state anorectal manometry. Anatomical and morphological changes can be assessed using defecography and 3D endorectal ultrasound. Electrical stimulation and biofeedback, pelvic floor exercises, rectal balloon training, transanal irrigation and sacral neuromodulation are all options for post-operative rehabilitation.
括约肌间切除术(ISR)已被作为一种终极保肛策略应用于部分低位直肠癌患者。越来越多的证据表明,ISR可能是腹会阴联合切除术的一个有意思的替代方案,可避免永久性造口,同时不影响肿瘤学结局。然而,肠功能障碍是ISR最常见的后果,不容忽视。迄今为止,根据患者报告结局测量方法报告功能和生活质量结局的临床研究有限。此外,由于缺乏高质量证据,关于低位前切除综合征管理的数据也很稀少。因此,本综述提供了对ISR患者系统评估(包括功能、生活质量、测压和形态学)及肠道康复的最新总结。术后肛门功能通常通过多种量表进行评估,包括失禁评估量表、胃肠功能问卷、特定的低位前切除综合征评估量表和粪便日记。特定疾病生活质量量表更适合用于评估ISR后大便失禁患者的生活质量。ISR术后患者的生理功能可通过水灌注或高分辨率固态肛门直肠测压进行评估。解剖学和形态学变化可通过排粪造影和三维直肠内超声进行评估。电刺激和生物反馈、盆底肌锻炼、直肠球囊训练、经肛门冲洗和骶神经调节都是术后康复的选择。