Palma Luiz Felipe, Campos Luana, Álvares Cristina Maria Arvate, Serrano Rafael Verardi, de Moraes Luís Otávio Carvalho
Department of Pathology, Federal University of São Paulo. São Paulo, SP, Brazil.
Graduate Program in Implantology, University of Santo Amaro, School of Dentistry, São Paulo, SP, Brazil.
J Lasers Med Sci. 2023 Jul 15;14:e21. doi: 10.34172/jlms.2023.21. eCollection 2023.
Alopecia areata (AA) is an autoimmune, inflammatory, non-scarring hair loss in which T-cells target hair follicles. Given that the available therapeutic options generally do not induce and sustain remission of AA effectively and many adverse effects may occur, monochromatic light sources have been recently gaining attention from clinicians. Therefore, the present paper aimed to report the first case in which photobiomodulation therapy (PBMT) with a continuous wave red laser (660 nm) was used as monotherapy for AA. An isolated round area of complete hair loss was subjected to daily PBMT sessions, resulting in significant regrowth (hair of normal coloration and thickness) within 7 days. On the 21 day, the patient's aesthetic concern was completely resolved. PBMT with a continuous wave red laser seems to be a promising therapeutic option for the treatment of AA; however, additional studies are necessary to obtain more robust evidence.
斑秃(AA)是一种自身免疫性、炎症性、非瘢痕性脱发,其中T细胞以毛囊为靶点。鉴于现有的治疗选择通常不能有效诱导和维持AA的缓解,并且可能会出现许多不良反应,单色光源最近受到了临床医生的关注。因此,本文旨在报告首例使用连续波红色激光(660nm)光生物调节疗法(PBMT)作为AA单一疗法的病例。对一个孤立的圆形完全脱发区域进行每日PBMT治疗,7天内毛发显著再生(颜色和厚度正常的毛发)。在第21天时,患者的美观问题得到完全解决。连续波红色激光PBMT似乎是治疗AA的一种有前景的治疗选择;然而,需要更多的研究来获得更有力的证据。