Tofani S, Agnesod G, Ossola P, Ferrini S, Bussi R
Health Phys. 1986 Oct;51(4):489-99. doi: 10.1097/00004032-198610000-00008.
To assess the effect of low-level radiofrequency radiation on pregnant rats, gravid dams were exposed continuously to 0.1 mW cm-2 at 27.12 MHz during different periods of pregnancy. Biological assays consisted of determining pre- and post-implantation losses and the effects on maternal body weight increase. Fetal parameters monitored included sex, mean viable fetal weight on Day 20 of gestation, external, skeletal and visceral fetal malformations, anomalies and variations. Dosimetric evaluations were made in terms of average specific absorption rate (SAR) and basal metabolic rate (BMR). Findings included a considerable increase in the percentage of total resorptions, reduced body weight increase in the exposed dams and incomplete cranial ossification in their fetuses. Results obtained were compared with those shown by other authors. It seems possible to ascribe some of the effects to a specific action of the radiofrequency radiation occurring independently of the rise in temperature. The hypothesis the exposure time, together with SAR, plays an important role in inducing specific exposure effects due to radiofrequency radiation is presented.
为评估低水平射频辐射对怀孕大鼠的影响,在孕期不同阶段,将妊娠母鼠连续暴露于27.12 MHz、0.1 mW/cm² 的环境中。生物学检测包括确定着床前和着床后的损失以及对母体体重增加的影响。监测的胎儿参数包括性别、妊娠第20天的平均存活胎儿体重、胎儿外部、骨骼和内脏畸形、异常及变异。剂量学评估依据平均比吸收率(SAR)和基础代谢率(BMR)进行。研究结果包括总吸收百分率显著增加、暴露母鼠体重增加减少以及胎儿颅骨骨化不完全。将所得结果与其他作者的结果进行了比较。似乎有可能将某些影响归因于射频辐射的特定作用,这种作用独立于温度升高而发生。本文提出了这样一种假设,即暴露时间与比吸收率一起,在诱发射频辐射的特定暴露效应方面起着重要作用。