Dorie M J, Kallman R F
Int J Radiat Oncol Biol Phys. 1986 Oct;12(10):1853-9. doi: 10.1016/0360-3016(86)90330-5.
The regrowth delay assay was used to assess hypoxic fraction in the RIF-1 tumor. Results approximating those of earlier paired survival curve data were obtained for previously untreated tumors and tumors treated with a single dose of 15 Gy. Further studies showed that after 5 daily fractions of 5 Gy, the hypoxic fraction returned to approximate pretreatment values within 24 hr.