Beitner R, Nordenberg J
Biochim Biophys Acta. 1979 Mar 7;583(2):266-9. doi: 10.1016/0304-4165(79)90434-3.
Glucose 1,6-bisphosphate, the powerful common regulator of several key enzymes in carbohydrate metabolism, was found to exert a potent inhibitory effect on the activity of 6-phosphogluconate dehydrogenase (decarboxylating) from yeast and several rat tissues. These findings suggest that glucose 1,6-bisphosphate may have a regulatory influence on the pentose phosphate pathway.
1,6-二磷酸葡萄糖是碳水化合物代谢中几种关键酶的强效共同调节剂,已发现它对酵母和几种大鼠组织中的6-磷酸葡萄糖酸脱氢酶(脱羧)活性具有强效抑制作用。这些发现表明,1,6-二磷酸葡萄糖可能对磷酸戊糖途径有调节作用。