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多发伤患者:当前概念与不断发展的治疗

The polytrauma patient: Current concepts and evolving care.

作者信息

Lee Christopher, Rasmussen Todd E, Pape Hans-Christoph, Gary Joshua L, Stannard James P, Haller Justin M

机构信息

Department of Orthopaedic Surgery, University of California - Los Angeles, Los Angeles, CA.

Department of General Surgery, F. Edward Hebert School of Medicine at the Uniformed Services University, Bethesda, MD.

出版信息

OTA Int. 2021 Apr 15;4(2 Suppl). doi: 10.1097/OI9.0000000000000108. eCollection 2021 Apr.

Abstract

Principles of care in the polytraumatized patient have continued to evolve with advancements in technology. Although hemorrhage has remained a primary cause of morbidity and mortality in acute trauma, emerging strategies that can be applied pre-medical facility as well as in-hospital have continued to improve care. Exo-vascular modalities, including the use of devices to address torso hemorrhage and areas not amenable to traditional tourniquets, have revolutionized prehospital treatment. Endovascular advancements including the resuscitative endovascular balloon occlusion of the aorta (REBOA), have led to dramatic improvements in systolic blood pressure, although not without their own unique complications. Although novel treatment options have continued to emerge, so too have concepts regarding optimal time frames for intervention. Though prior care has focused on Injury Severity Score (ISS) as a marker to determine timing of intervention, current consensus contends that unnecessary delays in fracture care should be avoided, while respecting the complex physiology of certain patient groups that may remain at increased risk for complications. Thromboelastography (TEG) has been one technique that focuses on the unique pathophysiology of each patient, providing guidance for resuscitation in addition to providing information in recognizing the at-risk patient for venous thromboembolism. Negative pressure wound therapy (NPWT) has emerged as a therapeutic adjuvant for select trauma patients with significant soft tissue defects and open wounds. With significant advancements in medical technology and improved understanding of patient physiology, the optimal approach to the polytrauma patient continues to evolve.

摘要

随着技术的进步,多发伤患者的护理原则也在不断演变。尽管出血仍然是急性创伤中发病和死亡的主要原因,但可在院前和院内应用的新策略不断改善护理。血管外治疗方式,包括使用解决躯干出血和传统止血带无法处理部位出血的装置,彻底改变了院前治疗。血管内治疗的进展,包括主动脉内复苏球囊阻断术(REBOA),显著提高了收缩压,尽管也有其独特的并发症。尽管新的治疗选择不断涌现,但关于最佳干预时间框架的概念也在不断发展。虽然以往的护理将损伤严重程度评分(ISS)作为确定干预时机的指标,但目前的共识认为,应避免骨折护理的不必要延迟,同时要考虑到某些患者群体复杂的生理状况,这些患者可能仍然有较高的并发症风险。血栓弹力图(TEG)是一种关注每个患者独特病理生理学的技术,除了为识别有静脉血栓栓塞风险的患者提供信息外,还为复苏提供指导。负压伤口治疗(NPWT)已成为治疗某些有严重软组织缺损和开放性伤口的创伤患者的辅助治疗方法。随着医学技术的显著进步和对患者生理状况的更好理解,多发伤患者的最佳治疗方法仍在不断演变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a96/10441682/d0506fc9974b/oi9-4-e108-g001.jpg

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