OBJECTIVE

The prevalence of kidney stones and their complications is high. The review of the literature showed the therapeutic effects of extract on urinary tract stones. This study reviewed the plant's hydroalcholic extract's effect on eliminating kidney and ureteral stones compared to hydrochlorothiazide.

MATERIALS AND METHODS

In this randomized prospective study, from March 2019 to September 2021, 80 patients over 18 years of age with kidney stones in the upper ureter with a size of 4-10 mm were divided into two groups based on the block random allocation method. The first group received hydrochlorothiazide tablets (50 mg), and the second group received 1 gram/day of the hydroalcholic areal extract of in a two-divided capsule. The mean size and number of stones, renal function tests, and side effects were checked and compared in both groups before and after the study.

RESULTS

Mean age, sex, serum urea level (=0.351), serum creatinine (=0.393), stone size (=0178), and the number of stones (=0.052) before intervention were similar. After intervention, the size and number of stones diminished, up to 70% in both groups. However, there was not a statistically significant difference between the two groups.

CONCLUSION

The study showed that is as effective as hydrochlorothiazide in treatment of kidney and ureteral stones with no significant complications and is promising.