Faculty of Medicine Department of Psychiatry, Dokuz Eylül University, Izmir, Turkey.
Department of Psychology, University of Sheffield, Sheffield, United Kingdom.
Psychol Med. 2024 Feb;54(3):558-568. doi: 10.1017/S0033291723002192. Epub 2023 Aug 23.
The incidence of psychotic disorders varies in different geographic areas. As there has been no report from Turkey, this study aimed to provide the treated incidence rate of first-episode psychosis (FEP) in a defined area.
All individuals, aged 15-64 years, presenting with FEP (ICD-10 F20-29, F30-33) to mental health services in a defined catchment-area in Sinop which is located in the Black Sea region of the northern Turkey were recorded over a 4-year period (2009 to 2012). Incidence rates of psychotic disorders and their 95% confidence intervals (CIs) were estimated. Poisson regression was applied to estimate the differences in incidence rate ratio (IRR) by age, sex, and urbanicity.
One hundred and fifteen FEP participants were identified during the 4 years. Crude incidence rates of all psychoses, schizophrenia, other psychotic disorders, and affective psychotic disorders were respectively 38.5 (95% CI 27.1-49.9), 10.7 (95% CI 6.6-14.8), 10.0 (95% CI 5.7-14.3) and 17.7 (95% CI 11.3-24.2) per 100 000 person-years. After age-sex standardisation the rates increased slightly. There were no gender differences in the incidence rates. IRR of any psychotic disorder was highest in the youngest age group (15-24 years) compared to the oldest age group (55-64 years), 7.9 (95% CI 2.8-30.5). In contrast with previous studies, the incidence rate of any psychotic disorder was not significantly increased in urban areas compared with rural areas.
The current study, the first of its kind from Turkey, indicates that the risk of schizophrenia and other psychotic disorders in a lowly urbanised area of Turkey is comparable to those reported in Western European cities.
精神病障碍的发病率在不同地理区域有所不同。由于土耳其尚无相关报告,本研究旨在提供一个特定区域内首次发作精神病(FEP)的治疗发病率。
在土耳其北部黑海南部的锡诺普,对在特定范围内的精神卫生服务机构就诊的年龄在 15-64 岁之间的所有 FEP(ICD-10 F20-29、F30-33)患者进行了为期 4 年(2009 年至 2012 年)的记录。估计了精神病障碍的发病率及其 95%置信区间(CI)。应用泊松回归估计年龄、性别和城市人口密度对发病率比(IRR)的差异。
在 4 年期间,共确定了 115 名 FEP 参与者。所有精神病、精神分裂症、其他精神病和情感性精神病的粗发病率分别为 38.5(95%CI 27.1-49.9)、10.7(95%CI 6.6-14.8)、10.0(95%CI 5.7-14.3)和 17.7(95%CI 11.3-24.2)/100000 人年。在年龄和性别标准化后,发病率略有上升。发病率在性别上没有差异。与最年长年龄组(55-64 岁)相比,任何精神病障碍的 IRR 在最年轻年龄组(15-24 岁)中最高,为 7.9(95%CI 2.8-30.5)。与先前的研究不同,与农村地区相比,任何精神病障碍的发病率在城市地区并没有显著增加。
这项来自土耳其的首例研究表明,在土耳其这个城市化程度较低的地区,精神分裂症和其他精神病障碍的风险与西欧城市报告的风险相当。