Martoccia Alessia, Al Salhi Yazan, Fuschi Andrea, Rera Onofrio Antonio, Suraci Paolo Pietro, Scalzo Silvio, Antonioni Alice, Valenzi Fabio Maria, Sequi Manfredi Bruno, De Nunzio Cosimo, Lombardo Riccardo, Sciarra Alessandro, Di Pierro Giovanni, Bozzini Giorgio, Asimakopoulos Anastasios D, Finazzi Agrò Enrico, Zucchi Alessandro, Gubiotti Marilena, Cervigni Mauro, Carbone Antonio, Pastore Antonio Luigi
Urology Unit, Department of Medical-Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine, "Sapienza" University of Rome, 04100 Latina, Italy.
Department of Urology, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Biomedicines. 2023 Jul 26;11(8):2105. doi: 10.3390/biomedicines11082105.
This study evaluated the effectiveness, safety, and possible changes in bowel symptoms after multicompartment prolapse surgery by comparing two different surgical approaches, transvaginal mesh surgery with levatorplasty (TVMLP) and robot-assisted sacrocolpopexy (RSC).
All patients underwent pelvic (POP-Q staging system) and rectal examination to evaluate anal sphincter tone in the lithotomy position with the appropriate Valsalva test. The preoperative evaluation included urodynamics and pelvic magnetic resonance defecography. Patient Global Impression of Improvement (PGI-I) at follow-up measured subjective improvement. All patients completed Agachan-Wexner's questionnaire at 0 and 12 months of follow-up to evaluate bowel symptoms.
A total of 73 cases were randomized into the RSC group (36 cases) and TVMLP group (37 cases). After surgery, the main POP-Q stage in both groups was stage I (RCS 80.5% vs. TVMLP 82%). There was a significant difference ( < 0.05) in postoperative anal sphincter tone: 35%. The TVMLP group experienced a hypertonic anal sphincter, while none of the RSC group did. Regarding subjective improvement, the median PGI-I was 1 in both groups. At 12 months of follow-up, both groups exhibited a significant improvement in bowel symptoms.
RSC and TVMLP successfully corrected multicompartment POP. RSC showed a greater improvement in the total Agachan-Wexner score and lower bowel symptoms.
本研究通过比较经阴道网片联合提肛肌成形术(TVMLP)和机器人辅助骶骨阴道固定术(RSC)这两种不同的手术方法,评估多腔室脱垂手术后的有效性、安全性以及肠道症状可能发生的变化。
所有患者均接受盆腔检查(POP-Q分期系统)和直肠检查,以在截石位通过适当的瓦尔萨尔瓦试验评估肛门括约肌张力。术前评估包括尿动力学检查和盆腔磁共振排粪造影。随访时的患者整体改善印象(PGI-I)用于衡量主观改善情况。所有患者在随访的0个月和12个月时完成阿加尚-韦克斯纳问卷,以评估肠道症状。
总共73例患者被随机分为RSC组(36例)和TVMLP组(37例)。手术后,两组的主要POP-Q分期均为I期(RCS组为80.5%,TVMLP组为82%)。术后肛门括约肌张力存在显著差异(<0.05):TVMLP组为35%。TVMLP组出现肛门括约肌张力亢进,而RSC组未出现。关于主观改善情况,两组的PGI-I中位数均为1。在随访12个月时,两组的肠道症状均有显著改善。
RSC和TVMLP均成功矫正了多腔室盆腔器官脱垂。RSC在阿加尚-韦克斯纳总分及肠道症状改善方面表现更佳。