Okamoto Y, Hayashi T, Harada K, Shojima K, Utsunomiya H, Maehara F, Yamamoto M
No Shinkei Geka. 1986 Jun;14(7):857-63.
A seven-year-old boy who was admitted for surgical treatment for intractable epilepsy was found to have a ganglioglioma in his left parietal lobe. Since four years old, he had been suffering from the seizure and treated with various anticonvulsants without satisfactory effects. As its frequency increased, the dose had to be increased. Thus, it was sought for the possible surgical approach. On the CT scans, an egg size low density zone without contrast enhancement was observed in the subcortical region of his parietal lobe. There was marked thinning on inner table of the skull immediately above the zone. He was operated under fronto-temporo-parietal craniotomy. When the dura matter was opened, pale cerebral cortex protruded. Complete removal of the tumor was not possible, since there was not clear boundary between the mass and normal tissue. Based on histological study, it was diagnosed as ganglioglioma, because its main body contained increased number of glia which had deeply stained ununiform size nuclei. After the operation, he showed neither motor paralysis nor sensory disturbance and was able to sustain his activity with less amount of anticonvulsant.
一名因顽固性癫痫入院接受手术治疗的七岁男孩，被发现左顶叶有一个神经节胶质瘤。自四岁起，他就遭受癫痫发作之苦，并用各种抗惊厥药物治疗，但效果不佳。随着发作频率增加，剂量不得不加大。因此，寻求可能的手术方法。在CT扫描中，在其顶叶皮质下区域观察到一个鸡蛋大小的无强化低密度区。该区域上方颅骨内板明显变薄。他接受了额颞顶开颅手术。打开硬脑膜时，苍白的大脑皮质突出。由于肿块与正常组织之间没有清晰边界，无法完全切除肿瘤。基于组织学研究，诊断为神经节胶质瘤，因为其主体包含数量增加的神经胶质细胞，这些细胞的细胞核大小不一且染色较深。手术后，他既没有运动麻痹也没有感觉障碍，并且能够用较少量的抗惊厥药物维持活动。
