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37 家威斯康星州奶牛场治疗临床乳腺炎的部分直接成本的差异。

Variation in partial direct costs of treating clinical mastitis among 37 Wisconsin dairy farms.

机构信息

Department of Animal Science, Michigan State University, East Lansing, MI 48824.

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824.

出版信息

J Dairy Sci. 2023 Dec;106(12):9276-9286. doi: 10.3168/jds.2023-23388. Epub 2023 Aug 23.

Abstract

The objective of this observational study was to describe variations in partial direct costs of clinical mastitis (CM) treatments among 37 dairy herds using data obtained from herd management records. Animal health and drug purchase records were retrospectively collected from 37 Wisconsin dairy herds for a period of 1 yr. Each farm was visited to verify case definitions, recording accuracy, and detection criteria of CM cases. Descriptive statistics were used to summarize cost of drugs and milk discard. Differences in costs among protocols, intramammary (IMM) products, parities, days in milk, and recurrence were analyzed using ANOVA. Of 20,625 cases of CM, 31% did not receive antimicrobial treatment. The average cost of drugs and milk discard (including cases that were not treated) was $192.36 ± 8.90 (mean ± SE) per case and ranged among farms from $118.13 to $337.25. For CM cases treated only with IMM antimicrobials, milk discard accounted for 87% of total costs and was highly influenced by duration of therapy. Differences in costs were observed among parities, recurrence, and stage of lactation at case detection. Eight different treatment protocols were observed, but 64% of cases were treated using only IMM antimicrobials. Treatment costs varied among protocols; however, cases treated using both IMM and injectable antimicrobials as well as supportive therapy had the greatest costs as they were also treated for the longest duration. Ceftiofur was used for 82% of cases that received IMM antimicrobials while ampicillin was used for 51% of cases treated using injectable antimicrobials. With the exception of ceftiofur and pirlimycin IMM products, many IMM products were given for durations that exceeded the maximum labeled duration. For cases treated using only IMM therapy, as compared with observed costs, we estimated that partial direct costs could be reduced by $65.20 per case if the minimum labeled durations were used. Overall, partial direct costs per case varied among herds, cow factors, and treatment protocols and were highly influenced by the duration of therapy.

摘要

本观察性研究的目的是,使用从牧场管理记录中获得的数据,描述 37 个奶牛场中临床型乳腺炎(CM)治疗的部分直接成本的变化。从威斯康星州的 37 个奶牛场收集了为期 1 年的动物健康和药物购买记录。每个牧场都进行了访问,以验证 CM 病例的定义、记录准确性和检测标准。使用描述性统计方法总结药物和牛奶丢弃的成本。使用方差分析(ANOVA)分析方案、内用(IMM)产品、胎次、泌乳天数和复发之间的成本差异。在 20625 例 CM 中,31%的病例未接受抗菌治疗。药物和牛奶丢弃(包括未治疗的病例)的平均成本为每例 192.36 ± 8.90 美元(平均值 ± SE),农场之间的范围为 118.13 至 337.25 美元。对于仅用 IMM 抗生素治疗的 CM 病例,牛奶丢弃占总成本的 87%,且受治疗持续时间的影响很大。胎次、复发和发病时泌乳阶段的成本差异。观察到了 8 种不同的治疗方案,但 64%的病例仅用 IMM 抗生素治疗。治疗成本因方案而异;然而,同时使用 IMM 和注射用抗生素以及支持性治疗的病例的成本最高,因为它们的治疗时间也最长。头孢噻呋用于 82%接受 IMM 抗生素治疗的病例,氨苄西林用于 51%接受注射用抗生素治疗的病例。除了头孢噻呋和吡利霉素 IMM 产品外,许多 IMM 产品的使用时间超过了最大标签持续时间。对于仅用 IMM 治疗的病例,如果使用最低标签持续时间,与观察到的成本相比,我们估计每例病例的部分直接成本可以降低 65.20 美元。总体而言,病例的部分直接成本在牧场、牛因素和治疗方案之间存在差异,且受治疗持续时间的影响很大。

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