Patlolla Sridhar Reddy, Devara Janaki, Ameer Muhammad Atif, Patlolla Prasanthy Reddy, Ponnala Madhusudhan
Hospital Medicine, Mission Hospital, Asheville, USA.
Internal Medicine, Mayo Clinic, Rochester, USA.
Cureus. 2023 Jul 28;15(7):e42594. doi: 10.7759/cureus.42594. eCollection 2023 Jul.
Diabetes Mellitus (DM) is a complex metabolic disease primarily associated with elevated blood glucose levels in the body. Diabetic ketoacidosis (DKA) is the most feared acute presentation of diabetes mellitus (DM) in both type 1 and type 2 diabetes mellitus. Furthermore, euglycemic diabetic ketoacidosis (EDKA) is a relatively rare complication of DM in which the blood glucose levels are usually less than 250 mg/dl with an elevated anion gap metabolic acidosis. It can be a diagnostic challenge due to normal blood glucose levels and often can be overlooked. Physicians should be aware of EDKA; prompt diagnosis and treatment are critical in the timely management of the condition to prevent complications. We present a case of EDKA in a 74-year-old female precipitated by a urinary tract infection which was identified and treated promptly with insulin and dextrose infusion. In addition to that, an important difference between British and American guidelines has been highlighted.
糖尿病(DM)是一种复杂的代谢性疾病,主要与体内血糖水平升高有关。糖尿病酮症酸中毒(DKA)是1型和2型糖尿病中最可怕的糖尿病急性表现。此外,正常血糖性糖尿病酮症酸中毒(EDKA)是糖尿病相对罕见的并发症,其血糖水平通常低于250mg/dl,伴有阴离子间隙代谢性酸中毒升高。由于血糖水平正常,它可能是一个诊断挑战,常常被忽视。医生应了解EDKA;及时诊断和治疗对于及时管理病情以预防并发症至关重要。我们报告一例74岁女性因尿路感染诱发的EDKA病例,该病例通过胰岛素和葡萄糖输注得到及时识别和治疗。除此之外,还强调了英国和美国指南之间的一个重要差异。