Adelaide Institute for Sleep Health, and FHRMI sleep health, Flinders University, South Australia, Australia.
School of Psychological Sciences and Health, University of Strathclyde, Glasgow, UK.
Curr Opin Pulm Med. 2023 Nov 1;29(6):567-573. doi: 10.1097/MCP.0000000000001007. Epub 2023 Aug 29.
Insomnia and obstructive sleep apnea have previously been viewed as completely independent conditions. However, there is now increasing recognition that insomnia and sleep apnea frequently co-occur. Co-morbid insomnia and sleep apnea (COMISA) is a highly prevalent condition that is associated with impairment of sleep, daytime function, mental health and physical health outcomes, and mortality risk. This review aims to provide an update on COMISA prevalence, consequences, treatment approaches, and future research directions.
People with COMISA experience worse sleep, mental health, physical health, quality of life and longevity compared to people with neither condition, and often compared to those with insomnia alone and sleep apnea alone. Emerging evidence suggests that cognitive behavioral therapy for insomnia is an effective treatment in the presence of treated and untreated sleep apnea, that may also improve manifestations and subsequent management of sleep apnea. Future research is required to understand the etiology of COMISA, and to develop and implement tailored treatment approaches.
It is important for sleep and respiratory technicians, researchers and clinicians to be aware of the high co-morbidity rates, consequences, and treatment requirements of patients with co-morbid insomnia and sleep apnea.
综述目的:过去,失眠和阻塞性睡眠呼吸暂停被认为是完全独立的疾病。然而,现在越来越多的人认识到失眠和睡眠呼吸暂停经常同时发生。共病性失眠和睡眠呼吸暂停(COMISA)是一种高发疾病,与睡眠、日间功能、心理健康和身体健康结果以及死亡风险受损有关。本综述旨在提供 COMISA 患病率、后果、治疗方法以及未来研究方向的最新信息。
最近的发现:与既无失眠也无睡眠呼吸暂停的人群相比,同时患有 COMISA 的人群的睡眠、心理健康、身体健康、生活质量和预期寿命更差,而且往往比仅患有失眠和仅患有睡眠呼吸暂停的人群更差。新出现的证据表明,对于治疗和未治疗的睡眠呼吸暂停,认知行为疗法治疗失眠是一种有效的治疗方法,也可能改善睡眠呼吸暂停的表现和后续管理。需要进一步研究来了解 COMISA 的病因,并制定和实施针对性的治疗方法。
综述总结:对于睡眠和呼吸技术人员、研究人员和临床医生来说,了解共病性失眠和睡眠呼吸暂停患者的高共病率、后果和治疗需求非常重要。