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墨西哥国家呼吸系统疾病研究所中重症新型冠状病毒肺炎患者的口腔病变：病例系列

Oral lesions in patients with severe COVID-19 in the National Institute of Respiratory Diseases in Mexico: Case series.

作者信息

Rueda Carlos Alberto Carrasco, Vinitzky Brener Ilan

机构信息

Oral and Maxillofacial Surgeon, Stomatology Department, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosio Villegas" Mexico City, México.

出版信息

J Dent Res Dent Clin Dent Prospects. 2023 Winter;17(1):54-60. doi: 10.34172/joddd.2023.37072. Epub 2023 Apr 3.

DOI:10.34172/joddd.2023.37072
PMID:37650015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10462920/
Abstract

Oral manifestations in patients with COVID-19 have already been reported in the literature. Determining whether the oral manifestations in these cases are directly related to SARS-CoV-2 infection or not has been challenging for both clinicians and researchers, although at present it has not been possible to prove. There are several possible causes for the development of the oral lesions in patients with COVID-19, among them are, opportunistic infections, drug reactions, iatrogenic and those directly related to viral infection. The present work describes the main characteristics of 10 severe COVID-19 hospitalized patients with oral manifestations. By analyzing the characteristics of the reported patients, and what is published in the literature, we conclude that for this series of cases the manifestations are not directly related to SARS-CoV-2, however, it is a possibility that should be considered for all patients.

摘要

COVID-19患者的口腔表现已有文献报道。确定这些病例中的口腔表现是否与SARS-CoV-2感染直接相关，对临床医生和研究人员来说一直具有挑战性，尽管目前还无法证实。COVID-19患者出现口腔病变有几种可能的原因，其中包括机会性感染、药物反应、医源性因素以及与病毒感染直接相关的因素。本研究描述了10例有口腔表现的COVID-19重症住院患者的主要特征。通过分析所报告患者的特征以及文献中发表的内容，我们得出结论，对于这一系列病例，这些表现与SARS-CoV-2没有直接关系，然而，所有患者都应考虑这种可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/d54e7e3cc66e/joddd-17-54-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/f9a4b1463c4f/joddd-17-54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/348f945b812e/joddd-17-54-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/b971e735b970/joddd-17-54-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/aa1bae81edeb/joddd-17-54-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/d54e7e3cc66e/joddd-17-54-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/f9a4b1463c4f/joddd-17-54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/348f945b812e/joddd-17-54-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/b971e735b970/joddd-17-54-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/aa1bae81edeb/joddd-17-54-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2d1/10462920/d54e7e3cc66e/joddd-17-54-g005.jpg

相似文献

[1]
Oral lesions in patients with severe COVID-19 in the National Institute of Respiratory Diseases in Mexico: Case series.

J Dent Res Dent Clin Dent Prospects. 2023

[2]
The spectrum of non-characteristic oral manifestations in COVID-19 - a scoping brief commentary.

Med Pr. 2021-12-22

[3]
COVID-19 and Its Repercussions on Oral Health: A Review.

Medicina (Kaunas). 2021-11-1

[4]
Is SARS-CoV-2 an Etiologic Agent or Predisposing Factor for Oral Lesions in COVID-19 Patients? A Concise Review of Reported Cases in the Literature.

Int J Dent. 2021-5-18

[5]
Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial.

Trials. 2020-10-28

[6]
COVID-19 and oral diseases: Assessing manifestations of a new pathogen in oral infections.

Int Rev Immunol. 2022

[7]
Oral Manifestations of COVID-19 in Hospitalized Patients: A Systematic Review.

Int J Environ Res Public Health. 2021-11-27

[8]
Pathogenesis-directed therapy of 2019 novel coronavirus disease.

J Med Virol. 2021-3

[9]
An update on oral clinical courses among patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A clinical follow-up (a prospective prevalent cohort) study.

PLoS One. 2022

[10]
COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic review.

Int J Dermatol. 2022-1

引用本文的文献

[1]
Unveiling the Oral Lesions, Dysgeusia and Osteonecrosis Related to COVID-19: A Comprehensive Systematic Review.

J Clin Med. 2025-2-14

[2]
Painful ulcerations associated with COVID-19 in an adolescent patient: a case report.

Front Dent Med. 2024-8-2

[3]
Awareness of undergraduate dental students, interns, and freshly graduated dentists about oral manifestation associated with COVID-19.

BMC Oral Health. 2023-12-9

本文引用的文献

[1]
Oral Manifestations of COVID-19 in Hospitalized Patients: A Systematic Review.

Int J Environ Res Public Health. 2021-11-27

[2]
Oral Manifestations of COVID-19: Updated Systematic Review With Meta-Analysis.

Front Med (Lausanne). 2021-8-25

[3]
Oral Manifestations in Patients with COVID-19: A 6-Month Update.

J Dent Res. 2021-11

[4]
Review of oral ulcerative lesions in COVID-19 patients: A comprehensive study of 51 cases.

J Dent Sci. 2021-10

[5]
Oral Manifestations in Patients with COVID-19: A Living Systematic Review.

J Dent Res. 2021-2

[6]
Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ?

Oral Surg Oral Med Oral Pathol Oral Radiol. 2021-2

[7]
Oral manifestations in a patient with a history of asymptomatic COVID-19: Case report.

Int J Infect Dis. 2020-9-1

[8]
Oral mucositis in a SARS-CoV-2-infected patient: Secondary or truly associated condition?

Oral Dis. 2022-4

[9]
Enanthem in Patients With COVID-19 and Skin Rash.

JAMA Dermatol. 2020-10-1

[10]
A case of erythema multiforme major in a patient with COVID 19: The role of corticosteroid treatment.

Dermatol Ther. 2020-11

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