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用于颊部麻醉的口腔局部麻醉注射疼痛缓解中,用氯乙烷喷雾进行冷冻麻醉与5%利多卡因凝胶的比较:一项随机临床(对照)试验。

Cryoanesthesia with ethyl chloride spray versus 5% lidocaine gel in alleviating oral local anesthetic injection pain for buccal anaesthesia: A randomized clinical (controlled) trial.

作者信息

Abbasi Hira, Ali Faiza, Aslam Hina, Khan Muhammad Sharjeel, Waqas Muhammad, Lal Abhishek

机构信息

Department of Operative Dentistry and Endodontics, Altamash Institute of Dental Medicine, Karachi, Pakistan.

Department of Dental Surgery, The Agha Khan University Hospital, Karachi, Pakistan.

出版信息

J Dent Res Dent Clin Dent Prospects. 2023 Winter;17(1):40-46. doi: 10.34172/joddd.2023.37041. Epub 2023 Apr 3.

DOI:10.34172/joddd.2023.37041
PMID:37650023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10462915/
Abstract

BACKGROUND

Numbing the area of oral mucosa with cold application prior to administration of regional anesthesia has been widely used by various dentists in alleviating pain caused by needle prick. Cryoanesthesia using Endo-ice as topical anesthesia has been studied as a replacement to prevail the fallibility of topical anaesthetics. This study aimed to evaluate and compare effectiveness of ethyl chloride spray with 5% lidocaine gel in alleviating buccal anesthesia injection pain.

METHODS

Total of 90 outpatients were randomly divided into 3 groups as follows: Group 1 - cryotherapy with ethyl chloride at the anesthetic site preceding before administration of local anesthesia; Group 2 - topical application of 5% LIDOCAINE GEL preceding before administration of local anesthesia; and group 3 - control that did not receive any topical agent preceding before administration of local anesthesia. Visual analogue scale (VAS) was used to document pain immediately after injection prick.

RESULTS

About comparison of pain scores, significant difference was found between group 1 (ethyl chloride) and group 2 (topical lidocaine) patients (=0.001). For group 1, about 15 (50%) patients suffered from mild pain, followed by 14 (46.67%) patients suffering from moderate pain. However, majority of the 21 (70%) patients in group 2 suffered from moderate pain. All the patients in group 3 suffered from severe pain.

CONCLUSION

Importance of alleviating fear of needle injection phobia amongst patients is of paramount importance. Ethyl chloride was found to be more effective than topical lidocaine in alleviating needle injection pain before administration of local anesthetic injection.

摘要

背景

在进行局部麻醉之前,用冷敷使口腔黏膜区域麻木,已被众多牙医广泛用于减轻针刺引起的疼痛。使用Endo-ice进行冷冻麻醉作为局部麻醉剂的替代方法,已被研究以克服局部麻醉剂的易误性。本研究旨在评估和比较氯乙烷喷雾剂与5%利多卡因凝胶在减轻颊部麻醉注射疼痛方面的有效性。

方法

总共90名门诊患者被随机分为3组,如下:第1组 - 在局部麻醉给药前,在麻醉部位用氯乙烷进行冷冻疗法;第2组 - 在局部麻醉给药前,局部应用5%利多卡因凝胶;第3组 - 对照组,在局部麻醉给药前不接受任何局部用药。使用视觉模拟量表(VAS)记录注射针刺后立即出现的疼痛情况。

结果

关于疼痛评分的比较,第1组(氯乙烷)和第2组(局部利多卡因)患者之间存在显著差异(=0.001)。对于第1组,约15名(50%)患者遭受轻度疼痛,其次是14名(46.67%)患者遭受中度疼痛。然而,第2组的21名患者中的大多数(70%)遭受中度疼痛。第3组的所有患者都遭受重度疼痛。

结论

减轻患者对注射针恐惧的重要性至关重要。发现在局部麻醉注射前,氯乙烷在减轻注射针疼痛方面比局部利多卡因更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/0b1d058f7bb3/joddd-17-40-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/9d8b8c554370/joddd-17-40-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/4eac48683c8f/joddd-17-40-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/c081145c0421/joddd-17-40-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/539abc42024c/joddd-17-40-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/0b1d058f7bb3/joddd-17-40-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/9d8b8c554370/joddd-17-40-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/4eac48683c8f/joddd-17-40-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/c081145c0421/joddd-17-40-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/539abc42024c/joddd-17-40-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32db/10462915/0b1d058f7bb3/joddd-17-40-g005.jpg

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