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住院戒毒治疗出院后预防自杀的简短策略的初步随机对照试验。

Pilot randomized controlled trial of a brief strategy to prevent suicide after discharge from residential addiction treatment.

机构信息

White River Junction VA Medical Center, 215 North Main Street, White River Junction, VT 05009, United States of America.

White River Junction VA Medical Center, 215 North Main Street, White River Junction, VT 05009, United States of America; Department of Psychiatry, Geisel School of Medicine, Dartmouth College, 1 Rope Ferry Road, Hanover, NH 03755, United States of America.

出版信息

J Subst Use Addict Treat. 2023 Nov;154:209156. doi: 10.1016/j.josat.2023.209156. Epub 2023 Aug 29.

Abstract

INTRODUCTION

Veterans are at greater risk for suicide and veterans with substance use disorder (SUD) have an even greater risk. Little research has looked into brief interventions to prevent suicide in this population in residential substance use treatment programs.

METHOD

We conducted a pilot, randomized controlled trial of a brief suicide prevention strategy called Veterans Affairs Brief Intervention and Contact Program (VA BIC) in patients participating in the Residential Recovery Center (RRC) SUD 28-day program and deemed at risk for suicide. We measured changes in symptoms at 1-, 3-, and 6-months. We looked at social connectedness, suicidal ideation, hopelessness, thwarted belongingness, perceived burdensomeness, and treatment engagement.

RESULTS

The study enrolled twenty patients. One participant withdrew immediately after baseline. We found that adherence to VA BIC components was high, as 100 % of patients (N = 10) completed 70 % or more of the VA BIC visits. Furthermore, 80 % of intervention group patients (N = 8) completed all VA BIC components. During the six-month follow-up, suicidal ideation improved in patients assigned to VA BIC, while it worsened in the standard care arm. Similarly, patients assigned to VA BIC reported a reduction in perceived burdensomeness over the six-month follow-up period while it worsened in the standard care arm. Additionally, VA BIC may modestly improve treatment engagement in the first month postdischarge.

CONCLUSION

We were able to recruit and enroll patients from a residential SUD treatment program into a clinical trial of the VA BIC intervention. Our preliminary results suggest that VA BIC may be useful in reducing suicidal ideation and perceived burdensomeness in patients who are discharged from residential SUD treatment programs and increasing treatment engagement. Future trials of VA BIC should determine whether VA BIC can reduce the risk of suicide in patients who are discharged from residential SUD treatment programs.

摘要

简介

退伍军人自杀的风险更高,而有物质使用障碍(SUD)的退伍军人的风险则更高。在住院物质使用治疗计划中,很少有研究关注针对这一人群的预防自杀的简短干预措施。

方法

我们对退伍军人事务部简短干预和联系计划(VA BIC)进行了一项试点、随机对照试验,该计划是一种预防自杀的简短策略,适用于参加住院康复中心(RRC)SUD 28 天项目且被认为有自杀风险的患者。我们在 1、3 和 6 个月时测量症状的变化。我们观察了社交联系、自杀意念、绝望、归属感受挫、被认为是负担、以及治疗参与度。

结果

该研究共纳入 20 名患者。一名参与者在基线后立即退出。我们发现 VA BIC 组件的依从性很高,因为 100%的患者(N=10)完成了 70%或更多的 VA BIC 访视。此外,干预组 80%的患者(N=8)完成了所有 VA BIC 组件。在六个月的随访期间,接受 VA BIC 治疗的患者的自杀意念有所改善,而接受标准护理的患者的自杀意念则恶化。同样,接受 VA BIC 治疗的患者在六个月的随访期间报告了感知负担的减轻,而接受标准护理的患者的感知负担则恶化。此外,VA BIC 可能会在出院后第一个月适度提高治疗参与度。

结论

我们能够从住院 SUD 治疗计划中招募和纳入患者参加 VA BIC 干预的临床试验。我们的初步结果表明,VA BIC 可能有助于减少从住院 SUD 治疗计划中出院的患者的自杀意念和感知负担,并增加治疗参与度。未来的 VA BIC 试验应确定 VA BIC 是否可以降低从住院 SUD 治疗计划中出院的患者的自杀风险。

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