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妊娠急性脂肪肝病例报告:肝脏疾病的疑难鉴别诊断

A Case Report on Acute Fatty Liver of Pregnancy: A Difficult Differential Diagnosis of Liver Disorder.

作者信息

Sinha Shivangni, Yadav Jyotsna, Pradhan Tarun

机构信息

Obstetrics and Gynecology, All India Institute of Medical Sciences Patna, Patna, IND.

Obstetrics and Gynecology, BP Koirala Institute of Medical Sciences, Dharan, NPL.

出版信息

Cureus. 2023 Jul 31;15(7):e42733. doi: 10.7759/cureus.42733. eCollection 2023 Jul.

Abstract

Acute fatty liver of pregnancy is a rare but potentially dangerous pregnancy condition with significant maternal and fetal fatality rates. The disorder is driven by a complex pathophysiology and clinically manifests as a rapid worsening in health conditions, increasing the rate of mortality and necessitating expert diagnosis and management. The condition progresses from spontaneous resolution to post-operative complications, resulting in negative consequences. We offer a case report of a young primigravida patient diagnosed with acute fatty liver of pregnancy at term. The report describes the clinical course and its effect. The perinatal result, however, could not be improved due to the late diagnosis. Over the last 40 years, death rates have been dramatically lowered because of competence and a multidisciplinary approach, increasing maternal-fetal outcomes. In this scenario, time management is crucial to success.

摘要

妊娠急性脂肪肝是一种罕见但潜在危险的妊娠疾病,母婴死亡率很高。这种疾病由复杂的病理生理学驱动,临床表现为健康状况迅速恶化,死亡率上升,需要专家进行诊断和管理。病情从自然缓解发展为术后并发症,会产生负面后果。我们提供了一例足月妊娠初产妇被诊断为妊娠急性脂肪肝的病例报告。该报告描述了临床过程及其影响。然而,由于诊断较晚,围产期结局未能得到改善。在过去40年里,由于专业能力和多学科方法,死亡率已大幅降低,母婴结局有所改善。在这种情况下,时间管理对成功至关重要。

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