Department of Psychiatry, University College Dublin, Ireland, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Orygen, Melbourne, VIC, Australia.
Soc Psychiatry Psychiatr Epidemiol. 2024 Jul;59(7):1143-1151. doi: 10.1007/s00127-023-02552-7. Epub 2023 Sep 3.
Individuals presenting with first episode psychosis (FEP) constitute a population with high admission rates. Across psychiatric services, community based treatment is aimed for where appropriate. Therefore, further knowledge on predictors of admission is required.
The objectives were to: (i) determine the proportion of individuals with FEP admitted at time of presentation (voluntarily and involuntarily) (ii) identify associated demographic and clinical factors.
This study included all young people (aged 15-24) who presented with FEP to the Early Psychosis Prevention and Intervention Centre, Melbourne, Australia from 01.01.11 to 31.12.16. Binary logistic regression was used to determine unadjusted and adjusted odds ratios.
Of 1208 participants, 58.6% were male and the median age was 20 years (I.Q.R.17-22). At time of presentation, 50.2% were admitted. On multivariate analysis, the following factors predicted admission: being a migrant (OR = 1.75, 95% CI [1.17, 2.62]), aggression (OR = 1.42, 95% CI [1.02, 1.99]), and more severe psychotic symptoms. Longer duration of untreated psychosis was associated with lower admission rates. 70.1% of admissions were involuntary (33.7% of the cohort). Risk factors for involuntary admission were consistent with any admission, other than aggression, and with the addition of older age and male sex.
There remains a high admission rate for FEP, even in an established early intervention service, with severity of psychopathology being the strongest predictive factor. There is an independent association between migrancy and admission. Potential reasons for these findings are discussed, and initiatives to reduce admission rates including (i) interventions to prevent admission and (ii) alternative care pathways.
首次出现精神病症状(FEP)的个体构成了高入院率人群。在所有精神科服务中,都以社区为基础进行治疗。因此,需要进一步了解入院的预测因素。
目的是:(i)确定在出现 FEP 时(自愿和非自愿)入院的个体比例;(ii)确定相关的人口统计学和临床因素。
这项研究包括所有于 2011 年 1 月 1 日至 2016 年 12 月 31 日在澳大利亚墨尔本早期精神病预防和干预中心就诊的 15-24 岁的 FEP 年轻人。采用二元逻辑回归确定未调整和调整后的优势比。
在 1208 名参与者中,58.6%为男性,中位年龄为 20 岁(IQR 17-22)。在就诊时,50.2%的患者被收治入院。多变量分析显示,以下因素预测入院:移民(OR=1.75,95%CI[1.17,2.62])、攻击行为(OR=1.42,95%CI[1.02,1.99])和更严重的精神病症状。未治疗的精神病症状持续时间较长与较低的入院率相关。70.1%的入院为非自愿(队列中的 33.7%)。非自愿入院的危险因素与任何入院相同,除了攻击行为,此外还与年龄较大和男性性别相关。
即使在既定的早期干预服务中,FEP 的入院率仍然很高,严重的精神病理学是最强的预测因素。移民与入院之间存在独立的关联。对这些发现的潜在原因进行了讨论,并提出了减少入院率的措施,包括(i)预防入院的干预措施,和(ii)替代护理途径。