Adham Marlinda, Dewi Dwi J, Reksodiputro Mirta Hediyati, Ranakusuma Respati
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Department of Clinical Epidemiology and Evidence Based Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Natl J Maxillofac Surg. 2023 May-Aug;14(2):334-338. doi: 10.4103/njms.njms_170_22. Epub 2023 Jan 17.
Ossifying fibroma (OF) in craniofacial is a rare disease, benign, locally aggressive fibro-osseous tumor. The 2017 World Health Organization classifications divided OF into two types: OF of odontogenic origin and juvenile ossifying fibroma (JOF). Determining the right surgical treatment to reduce the postoperative recurrence rate is incredibly challenging. The author reports two cases of paranasal sinuses with disease onset progressed from pre-pubertal age. The first case is an example of a recurrent case after undergoing conservative surgery, and the second is a new one. All cases underwent radical surgery with subtotal maxillectomy and reconstructive surgery in one stage. After observing all patients until one year, there was no sign of recurrence through clinical and endoscopic examination. There are two types of surgery that compare in this case report: conservative surgery and radical surgery. Conservative surgical procedures include curettage, enucleation, or peripheral osteotomies. Several studies have shown high recurrence levels in OF patients when curettage or enucleation is performed; residue caused by incomplete excision is the most common reason that is easily caused by conservative surgery. Radical surgery such as open maxillectomy is a promising approach for degrading the level of recurrence. JOF, especially trabecular juvenile ossifying fibroma, shows a high recurrence percentage comparing other types. The first-choice management for treating OF was the surgical approach. Types of surgery depend on the disease's aggressiveness and morbidity. Radical surgery was proven better at decreasing recurrence level than conservative surgery.
颅面部骨化性纤维瘤(OF)是一种罕见的、良性的、具有局部侵袭性的纤维骨性肿瘤。2017年世界卫生组织分类将OF分为两种类型:牙源性骨化性纤维瘤和青少年骨化性纤维瘤(JOF)。确定正确的手术治疗方法以降低术后复发率极具挑战性。作者报告了两例鼻窦OF病例,疾病均在青春期前发病。第一例是保守手术后复发的病例,第二例是初发病例。所有病例均一期行上颌骨次全切除根治性手术及重建手术。在对所有患者进行为期一年的观察后,通过临床和内镜检查未发现复发迹象。本病例报告比较了两种手术方式:保守手术和根治性手术。保守手术操作包括刮除术、摘除术或周边截骨术。多项研究表明,对OF患者进行刮除术或摘除术时复发率较高;保守手术容易导致的最常见原因是切除不完全造成的残留。诸如开放性上颌骨切除术等根治性手术是降低复发率的一种有前景的方法。JOF,尤其是小梁状青少年骨化性纤维瘤,与其他类型相比复发率较高。治疗OF的首选方法是手术。手术方式取决于疾病的侵袭性和发病率。事实证明,根治性手术在降低复发率方面比保守手术更好。