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好的,长期随访患者报告的结局、重返工作和重返运动率以及后交叉韧带(PCL)为基础的多韧带膝关节损伤(MLKI)合并后内侧角撕裂的生存率是失败的显著危险因素。

Good long-term patients reported outcomes, return-to-work and return-to-sport rate and survivorship after posterior cruciate ligament (PCL)-based multiligament knee injuries (MLKI) with posteromedial corner tears as significant risk factor for failure.

机构信息

Knee and Arthroscopy Unit, ICATME, Hospital Universitari Dexeus, Universitat Autònoma de Barcelona, Barcelona, Spain.

Clinica Ortopedica e Traumatologica II, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2023 Nov;31(11):5018-5024. doi: 10.1007/s00167-023-07547-0. Epub 2023 Sep 5.

Abstract

PURPOSE

To assess the survival rate and associated risk factors of a wide cohort of patient's underwent surgical treatment for posterior cruciate ligament (PCL)-based multiligament knee injury (MLKI) at long-term follow-up and to investigate the long-term patient's reported outcomes (PROMS) and functional activity.

METHODS

All cases of PCL-based MLKI performed at one single sport-medicine institution were extracted and patient's with a minimum 2 years of follow-up included. VAS, Lysholm, KOOS, Tegner Activity level scores, the incidence and time of return to sport (RTS) and return to work (RTW) were collected before, after surgery and at final follow-up. A multivariate logistic regression was performed to investigate the outcomes associated with the patient's acceptable symptoms state (PASS) for each sub-score of the KOOS. The Kaplan-Meier method with surgical failure (re-operation to one of the reconstructed ligaments) as endpoint was used to perform the survivorship analysis for the entire cohort.

RESULTS

Forty-two patients were included and evaluated at an average of 10 years. All PROMS significantly improved from pre- to post-surgery (range η 0.21-0.43, p < 0.05) except for the Tegner score which significantly improved from pre-surgery and to final follow-up (η = 0.67, p < 0.001). RTW was achieved in the 95.2% after 2.4 ± 1.9 months. RTS was achieved in 78.6% after 6.7 ± 5.0 months. The higher number of surgeries were the significant negative predictors of PASS for the KOOS sub-scales Sport (p = 0.040) and Quality of Life (p = 0.046), while the presence of meniscal lesions was a significant negative predictor of PASS only for the KOOS sub-scale of Sport (p = 0.003). Six patients (14.3%) underwent reoperation and were considered as surgical failures. The global survivorship was 95.2%, 92.6%, 87.1%, and 74.7% at 2, 5, 12, and 15 years, respectively. The survivorship in patient undergoing PMC reconstruction surgery was significantly lower (p = 0.004; HR 7.1) compared to patients without a PMC lesion.

CONCLUSION

Good-to-excellent PROMS could be obtained and maintained at long-term follow-up after surgery, with the higher number of surgeries and meniscal lesions as significant negative predictors of the PASS. Moreover, the presence of a PMC lesion significantly increases the risk of the PCL reconstruction failure.

LEVEL OF EVIDENCE

III.

摘要

目的

评估在长期随访中接受后交叉韧带(PCL)为基础的多韧带膝关节损伤(MLKI)手术治疗的广泛患者队列的生存率和相关风险因素,并调查长期患者报告的结果(PROMS)和功能活动。

方法

从一家运动医学机构提取所有基于 PCL 的 MLKI 病例,并纳入至少随访 2 年的患者。收集术前、术后和最终随访时的 VAS、Lysholm、KOOS、Tegner 活动水平评分、重返运动(RTS)和重返工作(RTW)的发生率和时间。进行多变量逻辑回归分析,以探讨 KOOS 各亚评分与患者可接受症状状态(PASS)相关的结果。以手术失败(重建韧带之一的再次手术)为终点,采用 Kaplan-Meier 法对整个队列进行生存分析。

结果

42 例患者平均随访 10 年。所有 PROMS 评分均从术前显著改善至术后(范围 η 0.21-0.43,p<0.05),除 Tegner 评分外,该评分从术前显著改善至最终随访(η=0.67,p<0.001)。术后 2.4±1.9 个月 RTW 达到 95.2%。术后 6.7±5.0 个月 RTS 达到 78.6%。手术次数越多,对 KOOS 运动亚量表(p=0.040)和生活质量亚量表(p=0.046)的 PASS 是显著的负预测因素,而半月板损伤的存在则是运动亚量表(p=0.003)PASS 的显著负预测因素。6 例(14.3%)患者接受再次手术,被认为手术失败。在 2、5、12 和 15 年时,总体生存率分别为 95.2%、92.6%、87.1%和 74.7%。接受 PMC 重建手术的患者的生存率明显较低(p=0.004;HR 7.1)。

结论

手术后长期随访可获得良好至优秀的 PROMS,手术次数和半月板损伤越多,PASS 的预测因素越差。此外,PMC 损伤的存在显著增加了 PCL 重建失败的风险。

证据水平

III。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca77/10598146/a34c81119574/167_2023_7547_Fig1_HTML.jpg

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