Infectious Diseases Unit, Pediatric Department, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Laboratório Nacional de Referência a Infeções Respiratórias a Agentes Bacterianos, Departamento de Doenças Infeciosas, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisbon, Portugal.
Euro Surveill. 2023 Sep;28(36). doi: 10.2807/1560-7917.ES.2023.28.36.2300427.
Since autumn 2022, observed numbers of paediatric invasive group A infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1 sublineage (26/55) and more diverse 12 isolates (12/55).
自 2022 年秋季以来,葡萄牙观察到的儿童侵袭性 A 组感染病例数(n=89)高于新冠疫情前的季节。2022 年 9 月至 2023 年 5 月期间,主要诊断为肺炎(79 例中的 25 例),其中大多数伴有脓胸(25 例中的 20 例)和败血症(79 例中的 22 例)。许多病例需要入住重症监护病房(79 例中的 27 例)和接受手术(79 例中的 35 例),病死率为 5.1%(79 例中的 4 例)。基因测序(n=55)显示存在多种基因谱系,以 M1 亚谱系为主(55 例中的 26 例),还有 12 个更具多样性的分离株(55 例中的 12 例)。