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弥漫性特发性骨肥厚患者轻微椎体骨折后继发进行性脊柱破坏:病例报告。

Progressive spinal destruction secondary to minimal vertebral fracture in a patient with diffuse idiopathic skeletal hyperostosis: a case report.

机构信息

Department of Rehabilitation Medicine, Osaka General Medical Center, Osaka, Japan.

Department of Rehabilitation Medicine, North Osaka Housenka Hospital, Osaka, Japan.

出版信息

J Int Med Res. 2023 Sep;51(9):3000605231194517. doi: 10.1177/03000605231194517.

Abstract

Early operative fixation is widely recognized as essential for managing spinal fractures in patients with diffuse idiopathic skeletal hyperostosis (DISH). However, no report to date has addressed the occurrence of minimal vertebral fractures diagnosable only through magnetic resonance imaging (MRI) in these patients and the associated temporal changes in the fracture site. In this report, we describe a rare clinical case involving an 81-year-old man who developed progressive spinal destruction secondary to a minimal vertebral fracture. MRI showed minimum-intensity changes in the T12 vertebral body, whereas X-ray and computed tomography examinations showed DISH and no spinal fracture. Despite experiencing severe low back pain, the patient did not undergo operative therapy for 2 months, resulting in progressive spinal destruction. Spinal fusion with posterior instrumentation was performed, and the patient was followed for 1 year with no symptoms and good functional status. This case emphasizes the importance of clinicians being cautious to avoid overlooking and undervaluing minimal vertebral fractures diagnosable only through MRI in patients with DISH.

摘要

早期手术固定被广泛认为是治疗弥漫性特发性骨肥厚症(DISH)患者脊柱骨折的必要手段。然而,迄今为止,尚无文献报道 DISH 患者中仅通过磁共振成像(MRI)可诊断出的微小椎体骨折的发生情况,以及骨折部位的相关时间变化。在本报告中,我们描述了一个罕见的临床病例,涉及一名 81 岁男性,因微小椎体骨折导致进行性脊柱破坏。MRI 显示 T12 椎体的 T1 加权像强度变化,而 X 射线和计算机断层扫描检查显示 DISH 但无脊柱骨折。尽管患者有严重的腰痛,但他在 2 个月内未接受手术治疗,导致脊柱进行性破坏。进行了后路器械固定的脊柱融合术,患者随访 1 年,无任何症状,功能状态良好。该病例强调了临床医生要谨慎,避免忽视和低估 DISH 患者仅通过 MRI 可诊断出的微小椎体骨折的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66f7/10492487/e45dc207ccea/10.1177_03000605231194517-fig1.jpg

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