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卵巢恶性肿瘤的皮肤转移:一例报告并文献复习

Skin Metastases in Ovarian Malignancy: A Case Report with Literature Review.

作者信息

Pipal Vibha Rani, Singh Pratibha, Pipal Dharmendra Kumar, Elhence Poonam

机构信息

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

出版信息

J Midlife Health. 2023 Jan-Mar;14(1):49-52. doi: 10.4103/jmh.jmh_137_22. Epub 2023 Jul 7.

Abstract

Ovarian cancer is the most lethal gynecologic malignancy, mostly diagnosed in the advanced stage with multiple sites of metastases. Routes of spread are direct through exfoliation, lymphatic channels, and less commonly hematogenous spread. Skin metastasis in ovarian malignancy is a rare occurence, its incidence range from 1.9% to 5.1% and the most common sites are the abdominal wall and chest wall. The incidence of metastasis to breast and/or axillary lymph nodes is very rare, ranging from 0.03% to 0.6%. We report the case of a 60-year-old female with stage IV B undifferentiated ovarian carcinoma with multiple cutaneous metastases involving the skin over the left breast, scalp, and mediastinal lymph nodes, which are rare sites of metastases. The incidence of cutaneous metastasis in ovarian cancer is 1.9%-5.1% and the overall survival after diagnosis ranges from 2 to 65 months.

摘要

卵巢癌是最致命的妇科恶性肿瘤,大多在晚期伴多处转移时被诊断出来。其传播途径包括通过脱落直接蔓延、经淋巴管传播,较少见的是血行传播。卵巢恶性肿瘤发生皮肤转移较为罕见,其发生率在1.9%至5.1%之间,最常见的部位是腹壁和胸壁。转移至乳房和/或腋窝淋巴结的发生率非常低,在0.03%至0.6%之间。我们报告一例60岁女性,患有IV B期未分化卵巢癌,伴有多处皮肤转移,累及左乳房上方皮肤、头皮和纵隔淋巴结,这些都是罕见的转移部位。卵巢癌皮肤转移的发生率为1.9% - 5.1%,诊断后的总生存期为2至65个月。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a04/10482014/17f8c3820016/JMH-14-49-g001.jpg

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