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原发性梗阻性巨输尿管的内镜球囊扩张术:是否需要荧光透视引导?

Endoscopic balloon dilation of primary obstructive megaureter: is fluoroscopic guidance necessary?

作者信息

Ortiz Rubén, Burgos Laura, Fernández-Bautista Beatriz, Parente Alberto, Ordóñez Javier, Angulo Jose María

机构信息

Pediatric Urology Division, Department of Pediatric Surgery, Hospital Universitario Gregorio Marañón, Madrid, Spain.

出版信息

World J Urol. 2023 Oct;41(10):2861-2867. doi: 10.1007/s00345-023-04572-z. Epub 2023 Sep 10.

Abstract

OBJECTIVE

To compare the long-term effectiveness, complications, and outcomes of primary obstructive megaureter (POM) treated by endoscopic balloon dilation under fluoroscopic guidance versus not using radioscopy during the procedure.

PATIENTS AND METHODS

A comparative study between POM cases treated at our institution by endoscopic balloon dilation (EBD) under fluoroscopic guidance (FG) (n = 43) vs no fluoroscopic guidance (NFG) (n = 48) between the years 2004 and 2018 was conducted. The procedure in FG consisted of performing a retrograde pyelography before dilation. Then, a guidewire is introduced to the renal pelvis, and the dilation of the vesicoureteral junction is performed using high-pressure balloon catheters under fluoroscopic vision. Finally, a double-J stent is placed between the renal pelvis and bladder. The procedure in NFG was performed exclusively under cystoscopic vision without radiological exposure. Complications, outcomes, and success rates were analyzed using Spearman's correlation test. Mean follow-up was 12.5 ± 2.2 years in FG and 6.4 ± 1.3 years in NFG.

RESULTS

MAG-3 showed significant differences in renal drainage before and after endoscopic treatment in both groups (p < 0.001 T-test). Statistical analysis did not reveal differences between groups in initial technical failure (r: - 0.035, p = 0.74), early postoperative complications (r: - 0.029, p = 0.79), secondary VUR (r: 0.033, p = 0.76), re-stenosis (r: 0.022, p = 0.84), long-term ureteral reimplantation (r: 0.065, p = 0.55), and final outcome (r: - 0.054, p = 0.61). The endoscopic approach of POM had a long-term success rate of 86.5% in FG VS 89.6% in NFG.

CONCLUSIONS

Endoscopic balloon dilation of POM can be done with no radiation exposure with similar results, effectiveness, and outcomes.

摘要

目的

比较在透视引导下进行内镜球囊扩张术治疗原发性梗阻性巨输尿管(POM)与术中不使用透视的长期疗效、并发症及治疗结果。

患者与方法

对2004年至2018年间在我院接受治疗的POM病例进行了一项对比研究,其中透视引导下(FG)内镜球囊扩张术(EBD)治疗组(n = 43),非透视引导(NFG)治疗组(n = 48)。FG组的操作包括在扩张前进行逆行肾盂造影。然后,将导丝引入肾盂,并在透视下使用高压球囊导管对膀胱输尿管连接部进行扩张。最后,在肾盂和膀胱之间放置双J支架。NFG组的操作完全在膀胱镜直视下进行,无放射暴露。使用Spearman相关性检验分析并发症、治疗结果及成功率。FG组平均随访时间为12.5±2.2年,NFG组为6.4±1.3年。

结果

两组内镜治疗前后MAG-3显示肾引流有显著差异(t检验,p < 0.001)。统计分析未显示两组在初始技术失败(r:-0.035,p = 0.74)、术后早期并发症(r:-0.029,p = 0.79)、继发性膀胱输尿管反流(r:0.033,p = 0.76)、再狭窄(r:0.022,p = 0.84)、长期输尿管再植(r:0.065,p = 0.55)及最终治疗结果(r:-0.054,p = 0.61)方面存在差异。POM的内镜治疗方法在FG组的长期成功率为86.5%,在NFG组为89.6%。

结论

POM的内镜球囊扩张术可不进行放射暴露,且结果、疗效和治疗结果相似。

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